Helicobacter Pylori infection and non-alcoholic fatty liver disease. Is there a relationship?

IF 0.2 Q4 HEALTH CARE SCIENCES & SERVICES
Neveen Rashad Mostafa, Abeer A. M. Ali, M. Alkaphoury, R. Marzo
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引用次数: 0

Abstract

The most prevalent infection that causes chronic gastritis, gastric ulcers, and gastric cancer is Helicobacter pylori infection. Recent research has implicated H. pylori in the pathogenesis of non-gastrointestinal diseases such as cardiovascular, autoimmune, and metabolic disorders. In addition, since H. pylori is believed to be implicated in insulin resistance, numerous studies have been conducted to determine the relationship between H. pylori infection and nonalcoholic fatty liver diseases (NAFLD), but the results have been contested. The purpose of this study is to determine the relationship between H. Pylori infection and nonalcoholic fatty liver diseases. One hundred patients were examined via urea breath test for the presence of H. pylori infection and vibration-controlled transient elastography for the diagnosis of non-alcoholic fatty liver disease. After adjusting for other variables, age, body mass index (BMI), and H. pylori infection were associated with elastography 248dB/m. Infection with H. pylori contributes to the development of NAFLD, and its eradication may influence prognosis.
幽门螺杆菌感染与非酒精性脂肪肝。有关系吗?
引起慢性胃炎、胃溃疡和胃癌的最常见的感染是幽门螺杆菌感染。最近的研究表明幽门螺杆菌与非胃肠道疾病如心血管、自身免疫和代谢紊乱的发病机制有关。此外,由于幽门螺杆菌被认为与胰岛素抵抗有关,已经进行了大量研究来确定幽门螺杆菌感染与非酒精性脂肪性肝病(NAFLD)之间的关系,但结果一直存在争议。本研究的目的是确定幽门螺杆菌感染与非酒精性脂肪肝之间的关系。通过尿素呼吸试验检查100例患者是否存在幽门螺杆菌感染,并通过振动控制瞬时弹性成像诊断非酒精性脂肪肝。在调整其他变量后,年龄、体重指数(BMI)和幽门螺杆菌感染与弹性成像248dB/m相关。幽门螺杆菌感染有助于NAFLD的发展,其根除可能影响预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.10
自引率
0.00%
发文量
13
审稿时长
10 weeks
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