Is There a Relationship Between Heroin Dependence and Anemia?

IF 1.1 Q3 Medicine
Bahadır Demir, A. Altındağ
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引用次数: 1

Abstract

Objective: We aimed to examine hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean cell hemoglobin concentration, red blood cell count (RBC), platelet count (PLT), ferritin, vitamin B12, and folic acid levels in heroin addicts by comparing them with healthy controls. Materials and Methods: This study included a total of 325 patients with only heroin use; and 163 healthy individuals. Participants, who had hematological disorders and other chronic diseases, were excluded from the study. HGB, HCT, MCV, mean cell hemoglobin concentration, RBC, PLT, ferritin, vitamin B12, and folic acid levels were compared between groups. Results: The patient group comprised of 318 males and 7 females with the mean age of 26.39±6.18 years. There was no significant difference between patient and control group in terms of age, sex, body mass index and alcohol consumption. HGB, HCT, folic acid levels, and RBC were lower in the patient group than control. There was no significant correlation among HGB, HCT, RBC, PLT, and the sociodemographic characteristics of patients. Conclusion: The effects of heroin on the hematological parameter should be considered. Heroin effects on HGB, HTC, RBC, and folic acid may tend to decrease. Prospective, longitudinal studies, and studies involving intoxication-remission periods are needed.
海洛因依赖与贫血有关系吗?
目的:检测海洛因依赖者血红蛋白(HGB)、红细胞压积(HCT)、平均红细胞体积(MCV)、平均细胞血红蛋白浓度、红细胞计数(RBC)、血小板计数(PLT)、铁蛋白、维生素B12和叶酸水平,并与健康对照进行比较。材料与方法:本研究共纳入325例仅使用海洛因的患者;163名健康人。患有血液病和其他慢性疾病的参与者被排除在研究之外。比较各组间HGB、HCT、MCV、平均细胞血红蛋白浓度、红细胞、血小板、铁蛋白、维生素B12、叶酸水平。结果:患者组男性318例,女性7例,平均年龄26.39±6.18岁。患者与对照组在年龄、性别、体重指数、饮酒量等方面无显著差异。患者组HGB、HCT、叶酸水平和RBC均低于对照组。HGB、HCT、RBC、PLT与患者的社会人口学特征无显著相关性。结论:海洛因对血液学指标的影响应引起重视。海洛因对HGB、HTC、RBC和叶酸的影响可能趋于降低。需要前瞻性、纵向研究和涉及中毒缓解期的研究。
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来源期刊
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期刊介绍: Addictive Disorders & Their Treatment is a quarterly international journal devoted to practical clinical research and treatment issues related to the misuses of alcohol and licit and illicit drugs and the study and treatment of addictive disorders and their behaviors. The journal publishes broad-spectrum, patient-oriented coverage of all aspects of addiction, directed toward an audience of psychiatrists, clinical psychologists, psychopharmacologists, and primary care practitioners. Original articles help clinicians make more educated, effective decisions regarding optimal patient management and care. In-depth reviews examine current understanding, diagnosis, and treatment of addiction disorders.
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