An unusual case of multisystem inflammatory syndrome in children in newborn due to covid-19 – presenting with stage 11 b necrotizing enterocolitis

IF 0.2 Q4 PEDIATRICS

Journal of Clinical Neonatology Pub Date : 2021-10-01 DOI:10.4103/jcn.jcn_78_21

N. Thakur, Narendra Rai

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引用次数: 3

Abstract

Neonatal enterocolitis is the most common gastrointestinal emergency reported in preterm babies. The most common infective organism involved in the pathogenesis includes bacteria such as Escherichia coli and Klebsiella. Until now, severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) as a causative agent of necrotizing enterocolitis (NEC) has not been reported. We report a unique case of multisystem inflammatory syndrome in children (MIS-C) and adolescents in newborn who presented with NEC. A 34-week-old male baby born to COVID-19-positive mother by normal vaginal delivery was admitted since birth in the special care newborn unit due to respiratory distress. Baby was COVID positive within 24 h of birth. He developed NEC at day 8 of life. He developed signs and symptoms of MIS-C. He responded to intravenous immunoglobulin and was discharged on day 16 of life. This is the first case report of MIS-C in newborn in India. Baby had NEC due to SARS-CoV2 which has not been reported until now. This case highlights the possibility of surge in newborn MIS-C postsecond wave of COVID-19 pandemic in India.

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新冠肺炎新生儿多系统炎症综合征的一例罕见病例——表现为11b期坏死性小肠结肠炎

新生儿小肠结肠炎是早产儿最常见的胃肠道急症。致病机制中最常见的感染性生物体包括大肠杆菌和克雷伯菌等细菌。到目前为止，作为坏死性小肠结肠炎（NEC）病原体的严重急性呼吸综合征冠状病毒2型（SARS-CoV2）尚未报道。我们报告了一例独特的新生儿多系统炎症综合征（MIS-C）和青少年NEC。一名新冠肺炎阳性母亲通过正常阴道分娩所生的34周大男婴因呼吸窘迫被送入特殊护理新生儿病房。婴儿在出生后24小时内呈新冠病毒阳性。他在生命的第8天患上了NEC。他出现了MIS-C的体征和症状。他对静脉注射免疫球蛋白有反应，在生命的第16天出院。这是印度首例新生儿MIS-C病例报告。婴儿因严重急性呼吸系统综合征冠状病毒2型而患NEC，目前尚未报道。该病例突显了印度第二波新冠肺炎大流行后新生儿MIS-C激增的可能性。

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Journal of Clinical Neonatology PEDIATRICS-

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期刊介绍： The JCN publishes original articles, clinical reviews and research reports which encompass both basic science and clinical research including randomized trials, observational studies and epidemiology.