Alzheimer Hastalığını Hafif Bilişsel Bozukluktan Ayırmak İçin Basit Bir MRI Tabanlı Görsel Kılavuz

Abstract

Objective: To distinguish between mild cognitive impairment (MCI) and Alzheimer’s disease (AD) by visual assessment of the length of the hippocampus in magnetic resonance imaging (MRI). Method: Consecutive patients diagnosed with MCI and AD were searched on the system retrospectively. MRI was rated for hippocampal atrophy defining with and without loss of hippocampal length. Patients with loss of hippocampal height were classified as having AD by the clinical investigator, and the diagnosis of the patients was checked on the system. Results: A total of 56 memory clinic patients with AD (n=14) and MCI (n=42) were included in the study. AD patients had significantly more hippocampal atrophy than MCI patients (𝜒2=6.222, df=0.13, 𝑝=0.013). Conclusion: There is a complex issue in the differential diagnosis between MCI and AD. A simple glace to the MRI may give a brief opinion to the physician in the clinic routine.