Association Of Triglyceride Glucose Index With Atherogenic Indices In Essential Hypertension

Abstract

Background and aim: Insulin resistance has been linked to both triglyceride-glucose index (TyG) and hypertension, and it is a major risk factor for cardiovascular disease. The present study aimed to determine the TyG index and atherogenic indices in essential hypertensive subjects and find out the association between them. Materials and Methods: In this case-control study, 250 patients with essential hypertension and 250 healthy controls were recruited and their serum lipids were analyzed using a Biosystem BA-400 chemistry analyzer. TyG index and atherogenic indices were calculated. Results: Triglyceride-glucose index was increased significantly in essential hypertension subjects compared to controls. All the atherogenic indices i.e. atherogenic index of plasma (AIP), cardiac risk ratio (CRR), and atherogenic coefficient (AC) were significantly increased in essential hypertensive subjects compared to controls. Additionally, the TyG index demonstrated a statistically significant positive association with the atherogenic index of plasma, cardiac risk ratio, and atherogenic coefficient in participants with essential hypertension. Conclusion: In conclusion, the TyG index was found to be positively associated with atherogenic indices in essential hypertension, suggesting essential hypertensive subjects are at increased risk for cardiovascular disease.