{"title":"High-resolution vat-photopolymerization of personalized bioceramic implants: new advances, regulatory hurdles, and key recommendations","authors":"I. Roohani, Ellen T. Newsom, H. Zreiqat","doi":"10.1080/09506608.2023.2194744","DOIUrl":null,"url":null,"abstract":"ABSTRACT Bioceramics are in high demand due to their biocompatibility and bone-regenerative properties, representing a multibillion-dollar industry with orthopaedic and dental implant applications. However, traditional manufacturing methods have limitations in producing complex geometries tailored to match patient-specific bone defects. Vat-photopolymerization 3D printing has emerged as a precise and high-resolution technique to fabricate complex bioceramic parts, generating strong, ultralight, energy-absorbing, and tough materials. Despite their promise, the clinical translation of 3D-printed bioceramic implants is hampered by regulatory and reimbursement hurdles. This review analyses recent advances in vat-photopolymerization printing of bioceramics, highlighting the technical challenges and the potential of nanoscale printing to enhance the mechanical and biological functions of implants. The review also provides recommendations for regulatory frameworks, envisioning a future with the successful clinical translation of advanced 3D architectures.","PeriodicalId":14427,"journal":{"name":"International Materials Reviews","volume":" ","pages":""},"PeriodicalIF":16.8000,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Materials Reviews","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1080/09506608.2023.2194744","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 3
Abstract
ABSTRACT Bioceramics are in high demand due to their biocompatibility and bone-regenerative properties, representing a multibillion-dollar industry with orthopaedic and dental implant applications. However, traditional manufacturing methods have limitations in producing complex geometries tailored to match patient-specific bone defects. Vat-photopolymerization 3D printing has emerged as a precise and high-resolution technique to fabricate complex bioceramic parts, generating strong, ultralight, energy-absorbing, and tough materials. Despite their promise, the clinical translation of 3D-printed bioceramic implants is hampered by regulatory and reimbursement hurdles. This review analyses recent advances in vat-photopolymerization printing of bioceramics, highlighting the technical challenges and the potential of nanoscale printing to enhance the mechanical and biological functions of implants. The review also provides recommendations for regulatory frameworks, envisioning a future with the successful clinical translation of advanced 3D architectures.
期刊介绍:
International Materials Reviews (IMR) is a comprehensive publication that provides in-depth coverage of the current state and advancements in various materials technologies. With contributions from internationally respected experts, IMR offers a thorough analysis of the subject matter. It undergoes rigorous evaluation by committees in the United States and United Kingdom for ensuring the highest quality of content.
Published by Sage on behalf of ASM International and the Institute of Materials, Minerals and Mining (UK), IMR is a valuable resource for professionals in the field. It is available online through Sage's platform, facilitating convenient access to its wealth of information.
Jointly produced by ASM International and the Institute of Materials, Minerals and Mining (UK), IMR focuses on technologies that impact industries dealing with metals, structural ceramics, composite materials, and electronic materials. Its coverage spans from practical applications to theoretical and practical aspects of material extraction, production, fabrication, properties, and behavior.