M. Raghuraman, A. Murugesan, D. Gurunathan, Daivam Indumathi, MThiriloga Sundary
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引用次数: 0
Abstract
Background: Lower concentrations of ropivacaine in continuous lumbar plexus block (LPB) have not been studied adequately. Thus, we designed this prospective, randomized, comparative study to evaluate the two different concentrations of ropivacaine (0.125% and 0.2%) in continuous LPB for postoperative pain relief following total hip arthroplasty (THA). Materials and Methods: Fifty patients undergoing THA under standardized subarachnoid block have been randomly allocated to receive a continuous infusion of either 0.125% (Group 1) or 0.2% (Group 2) of ropivacaine in LPB done under the guidance of peripheral nerve stimulator. The primary outcome was consumption of tramadol during the first 24 h and the secondary outcomes were quality of sensory and motor blockade and consumption of ropivacaine. Results: The total amount of tramadol did not differ significantly (P = 0.442) between the two groups. Furthermore, the duration of sensory and motor blockade did not differ significantly between the two groups. However, the average consumption of ropivacaine was significantly lower in Group 1 when compared to Group 2 (238.80 mg vs. 380.64 mg, P = 0.0001). Conclusion: Administration of 0.125% of ropivacaine can be a better alternative as it would decrease the total amount of the local anesthetic in continuous LPB.
背景:低浓度罗哌卡因在连续腰丛阻滞(LPB)中的应用尚未得到充分的研究。因此,我们设计了这项前瞻性、随机、比较研究,以评估两种不同浓度的罗哌卡因(0.125%和0.2%)在持续LPB中对全髋关节置换术(THA)术后疼痛的缓解作用。材料与方法:随机选取50例蛛网膜下腔阻滞下行THA的患者,在外周神经刺激器引导下进行LPB连续输注0.125%(组1)或0.2%(组2)罗哌卡因。主要结局是前24小时曲马多的消耗,次要结局是感觉和运动阻断的质量以及罗哌卡因的消耗。结果:两组患者曲马多用药总量差异无统计学意义(P = 0.442)。此外,感觉和运动阻滞的持续时间在两组之间没有显着差异。然而,与组2相比,组1的罗哌卡因平均消耗量显著降低(238.80 mg vs. 380.64 mg, P = 0.0001)。结论:0.125%的罗哌卡因可减少连续LPB的局麻药总量,是一种较好的选择。