Vitamin E protects rat testis, eye and erythrocyte from oxidative stress during exposure to radiofrequency wave generated by a BTS antenna model

Q4 Health Professions
G. Jelodar, A. Akbari, P. Parvaeei, S. Nazifi
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引用次数: 5

Abstract

Background: Radio frequency wave (RFW) generated by mobile phones and wireless communica on systems has been reported to cause adverse effects on reproduc ve func on, vision and hematological parameters, possibly through oxida ve stress. The aim of this study was to evaluate the effect of RFW generated bybase transceiver sta on BTS on oxida ve stress in tes s, eye and erythrocyte, and the prophylac c effect of vitamin E by measuring the an oxidant enzymes ac vity, including: glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT), and lipid proxida on. Materials and Methods: Thirty-two adult male Sprague–Dawley rats were randomly divided into four groups and treated daily for 45 days as follows: control, treatment control (vitamin E 200 mg/kg of body weight/ day by gavage), sham exposed group (exposed to 900 MHz RFW), and treatment group (received vitamin E and exposed to RFW). Control and treatment control groups were not exposed and were only given the vehicle, i.e., dis lled water. On the last day of the study, all the rats were sacrificed and their testes, eyes and erythrocyte were collected and used for measurement of an oxidant enzymes ac vity and lipid peroxida on. Results: Exposure to RFW in the sham exposed group decreased an oxidant enzymes ac vity and increased lipid peroxida on compared to both control groups (p<0.05). In the treatment group, vitamin E improved an oxidant enzymes ac vity and reduced lipid peroxida on compared to the sham exposed group (p<0.05). Conclusion: RFW causes oxida ve stress in eye, tes s and erythrocytes and vitamin E improved oxida ve stress in these ssues.
维生素E可以保护大鼠睾丸、眼睛和红细胞免受BTS天线模型产生的射频波的氧化应激
背景:据报道,手机和无线通信系统产生的射频波可能通过氧化应激对生殖功能、视力和血液学参数产生不良影响。本研究的目的是通过测定谷胱甘肽过氧化物酶(GPx)、超氧化物歧化酶(SOD)和过氧化氢酶(CAT)等氧化酶的活性,以及脂质proxida on,来评估基站收发器sta对BTS产生的RFW对眼睛和红细胞氧化应激的影响,以及维生素E的预防作用。材料和方法:32只成年雄性Sprague-Dawley大鼠随机分为四组,每天治疗45天,分别为:对照组、治疗组(维生素E 200mg/kg体重/天灌胃)、假暴露组(暴露于900MHz RFW)和治疗组(接受维生素E并暴露于RFW)。对照组和治疗对照组未暴露,仅给予赋形剂,即去离子水。在研究的最后一天,处死所有大鼠,收集睾丸、眼睛和红细胞,用于测量氧化酶活性和脂质过氧化。结果:与对照组相比,假暴露组暴露于RFW降低了氧化酶活性,增加了脂质过氧化(p<0.05),与假暴露组相比,维生素E提高了氧化酶活性,降低了脂质过氧化(p<0.05)。结论:RFW引起眼睛、tes和红细胞的氧化应激,维生素E改善了这些组织的氧化应激。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Iranian Journal of Radiation Research
Iranian Journal of Radiation Research RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
0.67
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: Iranian Journal of Radiation Research (IJRR) publishes original scientific research and clinical investigations related to radiation oncology, radiation biology, and Medical and health physics. The clinical studies submitted for publication include experimental studies of combined modality treatment, especially chemoradiotherapy approaches, and relevant innovations in hyperthermia, brachytherapy, high LET irradiation, nuclear medicine, dosimetry, tumor imaging, radiation treatment planning, radiosensitizers, and radioprotectors. All manuscripts must pass stringent peer-review and only papers that are rated of high scientific quality are accepted.
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