Mechanism of weather–related pain

Abstract

Chronic pain is known to get worse under the influence of weather change (tempera -ture, humidity, pressure). This is generally called “weather–related pain”. The author believes that the pressure sensor in the inner ear and the autonomic nervous system imbalance are involved in the mechanism of worsening pain and associated symptoms due to a decrease in atmospheric pressure. In addition, the activation mechanism of the cold receptor on skin occurs in chronic pain, which is considered to be the main role of the mechanism of aggravation of chronic pain under low tem perature environments.