Clinical Predictors of Duration of Untreated Psychosis: Exploring Psychosocial and Clinical Predictors of Duration of Untreated Psychosis in First-Episode Psychotic Patients in Mzuzu, Malawi.

IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Japhet Myaba, Charles M Mwale, Vincent C Jumbe
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引用次数: 0

Abstract

Introduction: The duration of untreated Psychosis (DUP) is a modifiable factor in the management and outcome of patients with psychosis. However, its predictive factors have not been studied much in Malawi. Our study was aimed at determining the psychosocial and clinical predictors of DUP in first episode psychosis in Malawi.

Method: A quantitative cross-sectional study, using secondary data from an early intervention study project was done in Mzuzu, Malawi. We analysed 140 adult participants enrolled in early intervention project in 2010. Data was collected using abstraction sheet to target predictive factors. We conducted univariate and multivariate logistic regression at confidence interval of 95%. We described the mean DUP, and looked at relationship of clinical and psychosocial factors with DUP.

Results: Most participants were male (60%, n=84) and single (51.4%, n=72). The median age of male participants was 31 years (Range=18 to 60), lower than females 35 years (Range=18 to 65). (what were the numbers of females). The majority of the participants' highest education level was secondary school (63.6%, n=89), and most had DUP of ≥ 6 months (74%, n=103). We found mean DUP of 42 months (SD= ±71). Employment status, diagnosis of schizophrenia (OR=10.93, 95% C.I 3.08-38.89), and negative symptoms of psychosis were associated with DUP of ≥ 6 months. Public self-consciousness and social quality of life were associated with long DUP.

Conclusion: Our study shows psychosocial and clinical factors that predict long DUP in Malawi. This highlights the need to target these factors when working on first episode psychosis for a better outcome.

未经治疗的精神病持续时间的临床预测因素:马拉维姆祖祖首次发作精神病患者未经治疗精神病持续期的心理社会和临床预测因素
未治疗精神病(DUP)的持续时间是精神病患者管理和预后的一个可改变的因素。然而,它的预测因素在马拉维还没有得到太多的研究。我们的研究旨在确定马拉维首发精神病患者DUP的社会心理和临床预测因素。方法采用定量横断面研究,使用马拉维Mzuzu早期干预研究项目的二手数据。我们分析了2010年参与早期干预项目的140名成年参与者。使用抽象表收集数据以确定预测因素。我们进行了单因素和多因素logistic回归,置信区间为95%。我们描述了平均DUP,并观察了临床和社会心理因素与DUP的关系。结果参与者以男性(60%,n=84)和单身(51.4%,n=72)居多。男性参与者的年龄中位数为31岁(范围为18 - 60岁),低于女性参与者的年龄中位数(范围为18 - 65岁)。(女性的数量是多少)。大多数参与者的最高学历为中学(63.6%,n=89),大多数参与者的DUP≥6个月(74%,n=103)。我们发现平均DUP为42个月(SD=±71)。就业状况、精神分裂症诊断(OR=10.93, 95% ci = 3.08-38.89)和精神疾病阴性症状与DUP≥6个月相关。公众自我意识和社会生活质量与长期DUP有关。结论:我们的研究表明,社会心理和临床因素预测长期DUP在马拉维。这突出了在治疗首发精神病时需要针对这些因素以获得更好的结果。
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来源期刊
Malawi Medical Journal
Malawi Medical Journal Medicine-General Medicine
CiteScore
1.50
自引率
0.00%
发文量
27
审稿时长
>12 weeks
期刊介绍: Driven and guided by the priorities articulated in the Malawi National Health Research Agenda, the Malawi Medical Journal publishes original research, short reports, case reports, viewpoints, insightful editorials and commentaries that are of high quality, informative and applicable to the Malawian and sub-Saharan Africa regions. Our particular interest is to publish evidence-based research that impacts and informs national health policies and medical practice in Malawi and the broader region. Topics covered in the journal include, but are not limited to: - Communicable diseases (HIV and AIDS, Malaria, TB, etc.) - Non-communicable diseases (Cardiovascular diseases, cancer, diabetes, etc.) - Sexual and Reproductive Health (Adolescent health, education, pregnancy and abortion, STDs and HIV and AIDS, etc.) - Mental health - Environmental health - Nutrition - Health systems and health policy (Leadership, ethics, and governance) - Community systems strengthening research - Injury, trauma, and surgical disorders
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