Factors related to healing time and scarring of herpes zoster in head and face

M. Wei, Wenge Fan, Qingsong Zhang, Jing Zhang, Q. Xue, Jun Zhao, Hao Ding, Ling-ling Wang
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Abstract

Objective To investigate the healing degree of lesions of herpes zoster in the head and face and the risk factor of the discosmetic sequelae. Methods 92 case of herpes zoster in the head and face were enrolled in this study. The patients were treated in dermatological clinic of Changshu No.1 People's Hospital from Jan. 2017 to Jun. 2018. The clinical data were recorded, such as the time of control, improving and healing of lesion, sex, age, position, the time of therapy starting and the behavior of scratching, extrusion and divest crust. The blood glucose and serum albumin of patients were measured. We observed the remained scars and performed statistic analysis. Results In diabetes group, the control and healing time was (2.40±1.28) d and (10.38±2.47) d respectively, meanwhile the control and healing time was (1.72±0.94) d and (8.32±2.66) d respectively in non-diabetes group (P<0.05). The single factor analysis indicated that the age, position, diabetes, lesion extrusion, divest crust were the correlation factors of the zoster scar in head and face (P<0.05). Nevertheless the multifactor logistic regression indicated that the position, diabetes and divest crust were independent risk factors of the zoster scar in head and face (P<0.05). Conclusions The healing of herpes zoster is affected by diabetes. The independent risk factors of zoster scar in head and face are non-trigeminal nerves positions, diabetes and divest crust. Key words: Herpes zoster; Cicatrix; Risk factors; Diabetes mellitus; Hypoalbuminemia
头部和面部带状疱疹愈合时间和瘢痕形成的相关因素
目的探讨头面部带状疱疹病变的愈合程度及并发后遗症的危险因素。方法对92例头部、面部带状疱疹患者进行研究。患者于2017年1月至2018年6月在常熟市第一人民医院皮肤科门诊就诊。记录患者的临床资料,如病灶控制时间、改善时间、愈合时间、性别、年龄、体位、治疗开始时间、搔抓、挤压、剥皮行为等。测定患者的血糖和血清白蛋白。观察残余疤痕并进行统计分析。结果糖尿病组的对照组和愈合时间分别为(2.40±1.28)d和(10.38±2.47)d,非糖尿病组的对照组和愈合时间分别为(1.72±0.94)d和(8.32±2.66)d (P<0.05)。单因素分析显示,年龄、体位、糖尿病、病变挤压、剥离结皮是头面部带状疱疹瘢痕的相关因素(P<0.05)。多因素logistic回归分析显示,体位、糖尿病、剥皮是头面部带状疱疹瘢痕发生的独立危险因素(P<0.05)。结论糖尿病影响带状疱疹的愈合。头面部带状瘢痕的独立危险因素为非三叉神经位置、糖尿病和剥皮。关键词:带状疱疹;叶痕;风险因素;糖尿病;低白蛋白血症
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来源期刊
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4641
期刊介绍: "Chinese Journal of Medical Aesthetics and Cosmetology" is a high-end academic journal focusing on the basic theoretical research and clinical application of medical aesthetics and cosmetology. In March 2002, it was included in the statistical source journals of Chinese scientific and technological papers of the Ministry of Science and Technology, and has been included in the full-text retrieval system of "China Journal Network", "Chinese Academic Journals (CD-ROM Edition)" and "China Academic Journals Comprehensive Evaluation Database". Publishes research and applications in cosmetic surgery, cosmetic dermatology, cosmetic dentistry, cosmetic internal medicine, physical cosmetology, drug cosmetology, traditional Chinese medicine cosmetology and beauty care. Columns include: clinical treatises, experimental research, medical aesthetics, experience summaries, case reports, technological innovations, reviews, lectures, etc.
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