Assessment of Elderly Type 2 Diabetic Patients who Self-adjust Their Insulin Regimen in Al-Qassim Region

M. Alharbi, Turki Alrashidi, M. Al-Harbi, Essa Al Zahrani, Mohammed H. Alkahlot, Mohammed S Aljaberi
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Abstract

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a multifactorial chronic disease. To avoid long-term and short-term complications, good glycemic control must be achieved. The majority of T2DM patients who require insulin therapy have their doses modified by their physicians; this procedure takes time and may not result in the optimal glycemic control. AIM: This study aims to ascertain whether elderly T2DM patients in Al-Qassim region modify their own insulin regimen and its effect on their glycemic control. METHODS: This cross-sectional study was conducted in Al-Qassim University Medical City and Diabetic Centers in Buraydah, Saudi Arabia. Data were collected using a questionnaire. RESULTS: A total of 384 participants were enrolled with a mean age of 70.2 ± 6.0 (61–94) years, majority (53.6%) of whom were females. About half (50.8%) were not educated and two-third (66.1%) giving insulin injections by themselves. Less than half (40.6%) of the participants changed their insulin dose, out of which 8.3% changed the dose by themselves. The mean hemoglobin A1C (HbA1c) level was 8.8 ± 1.9 with a range of 5.2–17. About 30.5% had recent hypoglycemic attacks, majority (47.9%) of whom had only one episode. Diabetic complications were seen among 127 participants with retinopathy as the most common (43.3%) complication. Hypoglycemic attacks and insulin dose adjusting were not found to be significantly associated (p = 0.476). The last HbA1c level was found to be significantly associated with adjusting insulin dose. CONCLUSION: Self-adjusting insulin dose was found to be rare. Moreover, HbA1c in patients who self-adjust their insulin dose was found to be significantly lower.
老年2型糖尿病患者自我调节胰岛素方案的评估
背景:2型糖尿病(T2DM)是一种多因素慢性疾病。为了避免长期和短期的并发症,必须达到良好的血糖控制。大多数需要胰岛素治疗的2型糖尿病患者的剂量由他们的医生修改;这个过程需要时间,可能无法达到最佳的血糖控制。目的:本研究旨在了解Al-Qassim地区老年T2DM患者是否改变自身胰岛素治疗方案及其对血糖控制的影响。方法:本横断面研究在沙特阿拉伯Buraydah的Al-Qassim大学医学城和糖尿病中心进行。通过问卷调查收集数据。结果:共纳入384名参与者,平均年龄为70.2±6.0(61-94)岁,其中大多数(53.6%)为女性。约一半(50.8%)未接受教育,三分之二(66.1%)自行注射胰岛素。不到一半(40.6%)的参与者改变了他们的胰岛素剂量,其中8.3%的人自己改变了剂量。平均糖化血红蛋白(HbA1c)水平为8.8±1.9,范围为5.2 ~ 17。约30.5%近期有过低血糖发作,其中大多数(47.9%)仅发生过一次低血糖发作。127名视网膜病变患者中,糖尿病并发症是最常见的并发症(43.3%)。低血糖发作与胰岛素剂量调整无显著相关性(p = 0.476)。最后的HbA1c水平与胰岛素剂量的调整显著相关。结论:自我调节胰岛素剂量的情况比较少见。此外,发现自我调整胰岛素剂量的患者的HbA1c显著降低。
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来源期刊
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期刊介绍: Open Access Macedonian Journal of Medical Sciences (OAMJMS) [formerly known as Macedonian Journal of Medical Sciences] is a top-tier open access medical science journal published by the ID Design 2012/DOOEL Skopje, Rajko Zhinzifov No 48, 1000 Skopje, Republic of Macedonia. OAMJMS is an international, modern, general medical journal covering all areas in the medical sciences, from basic studies to large clinical trials and cost-effectiveness analyses. We publish mostly human studies that substantially enhance our understanding of disease epidemiology, etiology, and physiology; the development of prognostic and diagnostic technologies; trials that test the efficacy of specific interventions and those that compare different treatments; and systematic reviews. We aim to promote translation of basic research into clinical investigation, and of clinical evidence into practice. We publish occasional studies in animal models when they report outstanding research findings that are highly clinically relevant. Our audience is the international medical community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world. OAMJMS is published quarterly online version. The Open Access Macedonian Journal of Medical Sciences (OAMJMS) publishes Medical Informatics, Basic Science, Clinical Science, Case Report, Brief Communication, Public Health, Public Policy, and Review Article from all fields of medicine and related fields. This journal also publishes, continuously or occasionally, the bibliographies of the members of the Society, medical history, medical publications, thesis abstracts, book reviews, reports on meetings, i­n­formation on future meetings, important events and dates, and various headings which contribute to the development of the corresponding scientific field.
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