Magnesium deficiency and COVID- 19 – What are the links?

IF 0.1 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trace Elements and Electrolytes Pub Date : 2020-07-01 DOI:10.5414/tex01651

O. Micke, J. Vormann, K. Kisters

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引用次数: 11

Abstract

DOI 10.5414/TEX01651 e-pub: June 25, 2020 *President of the German Society for Magnesium Research e.V. **Vice-President of the Society for Magnesium Research e.V. The novel coronavirus SARS-CoV-2 is causing an ongoing worldwide pandemic of COVID-19. The infection with this single-stranded RNA virus appears to be asymptomatic in a large fraction of people, and many other patients may experience mild symptoms such as fever, cough, anosmia, and myalgia. Some German patients need hospitalization, and some will develop acute respiratory distress syndrome (ARDS), and a significant subset will require treatment in the intensive care unit to provide respiratory ventilator support. Unfortunately, there is no causal curative treatment or a vaccination available, so far. In this context, the potential prophylactic and therapeutic options for the novel SARS-CoV-2 infection and corresponding COVID-19, as well as interventions with special nutrients like zinc or vitamin D are discussed, especially due to their role in the immune system [1, 2, 3, 4]. Magnesium (Mg) has a strong relation with the immune system as well, and immunological functions are disturbed in case of Mg deficiency [5, 6]. Interestingly, in patients with XMEN disease (X-linked immunodeficiency with Mg defect, Epstein-Barr virus (EBV) infection, Magnesium deficiency and COVID-19 – What are the links? Some remarks from the German Society for Magnesium Research e.V.

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缺镁和COVID- 19之间有什么联系?

德国镁研究协会主席**镁研究协会副主席新型冠状病毒SARS-CoV-2正在引起全球范围内持续的COVID-19大流行。感染这种单链RNA病毒的大部分人似乎没有症状，许多其他患者可能出现轻微症状，如发烧、咳嗽、嗅觉丧失和肌痛。一些德国患者需要住院治疗，一些患者将发展为急性呼吸窘迫综合征(ARDS)，并且一个重要的子集将需要在重症监护病房接受治疗，以提供呼吸机支持。不幸的是，到目前为止，没有因果治疗或疫苗可用。在此背景下，本文讨论了新型SARS-CoV-2感染和相应的COVID-19的潜在预防和治疗方案，以及锌或维生素D等特殊营养素的干预措施，特别是考虑到它们在免疫系统中的作用[1,2,3,4]。镁(Mg)与免疫系统也有很强的关系，缺镁会影响免疫功能[5,6]。有趣的是，在XMEN疾病(x连锁免疫缺陷伴Mg缺陷、eb病毒感染、缺镁和COVID-19)患者中，它们之间有什么联系?德国镁研究协会的一些评论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trace Elements and Electrolytes 生物-内分泌学与代谢

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Trace elements and Electrolytes appears quarterly and publishes reviews and editorials, original papers, short communications, and reports on recent advances in the entire field of trace elements. Papers on experimental findings are accepted if they bear a close relationship to human diseases. Correspondence (letters to the editors) and current information including book announcements will also be published.