Current state-of-the-art review of nanotechnology-based therapeutics for viral pandemics: Special attention to COVID-19

IF 6.1 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY
M. Motiei, L. Lucia, Tomáš Sáha, Petr Sáha
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Abstract

Abstract Over the past two centuries, most pandemics have been caused by zoonotic RNA viruses with high mutation, infection, and transmission rates. Due to the importance of understanding the viruses’ role in establishing the latest outbreak pandemics, we briefly discuss their etiology, symptomatology, and epidemiology and then pay close attention to the latest chronic communicable disease, SARS-CoV-2. To date, there are no generally proven effective techniques in the diagnosis, treatment, and spread strategy of viral diseases, so there is a profound need to discover efficient technologies to address these issues. Nanotechnology can be a promising approach for designing more functional and potent therapeutics against coronavirus disease 2019 (COVID-19) and other viral diseases. Moreover, this review intends to summarize examples of nanostructures that play a role in preventing, diagnosing, and treating COVID-19 and be a comprehensive and helpful review by covering notable and vital applications of nanotechnology-based strategies for improving health and environmental sanitation. Graphical abstract Nanotechnology is a promising approach for preventing, diagnosing, and treating COVID-19 and related viral diseases.
基于纳米技术的病毒大流行治疗的最新进展综述:特别关注COVID-19
摘要在过去的两个世纪里,大多数流行病都是由具有高突变率、高感染率和高传播率的人畜共患RNA病毒引起的。由于了解病毒在建立最新爆发的流行病中的作用的重要性,我们简要讨论了它们的病因、症状学和流行病学,然后密切关注最新的慢性传染病严重急性呼吸系统综合征冠状病毒2型。到目前为止,在病毒性疾病的诊断、治疗和传播策略方面,还没有公认的有效技术,因此迫切需要发现有效的技术来解决这些问题。纳米技术可以成为一种很有前途的方法,用于设计针对2019冠状病毒病(新冠肺炎)和其他病毒性疾病的更具功能性和效力的治疗方法。此外,本综述旨在总结在预防、诊断和治疗新冠肺炎中发挥作用的纳米结构的例子,并通过涵盖基于纳米技术的改善健康和环境卫生战略的显著和重要应用,成为一篇全面而有帮助的综述。纳米技术是预防、诊断和治疗新冠肺炎及相关病毒性疾病的一种很有前途的方法。
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来源期刊
Nanotechnology Reviews
Nanotechnology Reviews CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTECHNOLOGY
CiteScore
11.40
自引率
13.50%
发文量
137
审稿时长
7 weeks
期刊介绍: The bimonthly journal Nanotechnology Reviews provides a platform for scientists and engineers of all involved disciplines to exchange important recent research on fundamental as well as applied aspects. While expert reviews provide a state of the art assessment on a specific topic, research highlight contributions present most recent and novel findings. In addition to technical contributions, Nanotechnology Reviews publishes articles on implications of nanotechnology for society, environment, education, intellectual property, industry, and politics.
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