Placental development research: breakthrough and prospect

Q4 Medicine

中华围产医学杂志 Pub Date : 2019-10-16 DOI:10.3760/CMA.J.ISSN.1007-9408.2019.10.003

Xuan Shao

引用次数: 1

Abstract

Successful pregnancy and delivery of a healthy offspring largely rely on a well-developed placenta. Defects in placental development may lead to various pregnancy complications. However, placenta has been one of the least understood organs. The mechanism of its development and function, as well as the molecular association between placental disorders and pregnancy complications remain unclear, thus become the least known area in the exploration of pregnancy and life. Along with the advances in modern techniques, the understanding of the placenta has been deepened from tissue structure to cellular and molecular level, and gradually toward the omics and systematic biology. In recent years, a number of groundbreaking achievements have been made in the field of placental development, which were summarized in this article. Some relevant international funding programs and future prospects in this area were also discussed. Key words: Placentation; Health planning support; Pregnancy complications

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胎盘发育研究:突破与展望

成功怀孕和产下健康的后代在很大程度上依赖于发育良好的胎盘。胎盘发育缺陷可导致各种妊娠并发症。然而，胎盘一直是最不为人知的器官之一。其发育和功能的机制以及胎盘紊乱与妊娠并发症的分子关联尚不清楚，因此成为探索妊娠和生命的最不为人知的领域。随着现代技术的进步，对胎盘的认识已从组织结构深入到细胞和分子水平，并逐渐向组学和系统生物学方向发展。近年来，在胎盘发育领域取得了一些突破性的成果，本文对这些成果进行了总结。并对相关国际资助项目进行了展望。关键词:胎盘;保健规划支助;妊娠并发症

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来源期刊

中华围产医学杂志 Medicine-Obstetrics and Gynecology

CiteScore

0.70

自引率

0.00%

发文量

4446

期刊介绍： Chinese Journal of Perinatal Medicine was founded in May 1998. It is one of the journals of the Chinese Medical Association, which is supervised by the China Association for Science and Technology, sponsored by the Chinese Medical Association, and hosted by Peking University First Hospital. Perinatal medicine is a new discipline jointly studied by obstetrics and neonatology. The purpose of this journal is to "prenatal and postnatal care, improve the quality of the newborn population, and ensure the safety and health of mothers and infants". It reflects the new theories, new technologies, and new progress in perinatal medicine in related disciplines such as basic, clinical and preventive medicine, genetics, and sociology. It aims to provide a window and platform for academic exchanges, information transmission, and understanding of the development trends of domestic and foreign perinatal medicine for the majority of perinatal medicine workers in my country.