Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report

Glioma Pub Date : 2021-07-01 DOI:10.4103/glioma.glioma_13_21
P. Aggarwal, D. Chatterjee, V. Gupta, Rekha Gupt
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引用次数: 0

Abstract

Epithelioid glioblastoma (eGB) is an uncommon morphological variant of isocitrate dehydrogenase wild-type GB that commonly presents as a cerebral mass in young adults and children. Here, we report the case of a 22-year-old man who presented with a cerebellar tumor. With the provisional diagnosis of pilocytic astrocytoma and adult medulloblastoma, he underwent suboccipital craniotomy with gross total excision of the tumor. On histopathological examination, he was diagnosed with eGB. Cerebellar presentation of eGB is a rare event that has not been previously described in the literature. The present case also highlights the need for differentiating eGB from its morphological mimics by carefully interpreting histopathological and immunohistochemical examination findings.
小脑上皮样胶质母细胞瘤的诊断挑战:一例报告
上皮样胶质母细胞瘤(eGB)是异柠檬酸脱氢酶野生型GB的一种不常见的形态变体,通常在年轻成人和儿童中表现为脑肿块。在这里,我们报告了一个22岁的男子,他表现为小脑肿瘤。根据毛细胞星形细胞瘤和成人髓母细胞瘤的临时诊断,他接受了枕下开颅手术,并对肿瘤进行了全面切除。在组织病理学检查中,他被诊断为eGB。eGB的小脑表现是一种罕见的事件,以前在文献中没有描述过。本病例还强调了通过仔细解释组织病理学和免疫组织化学检查结果来区分eGB与其形态学模拟物的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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审稿时长
42 weeks
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