Organocatalytic C-H Bond Functionalizations for the Synthesis of Heterocycles

IF 0.9 Q4 CHEMISTRY, PHYSICAL
Biswajit Panda
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引用次数: 0

Abstract

Organocatalysis is an important and rapidly growing area for the synthesis of various organic molecules. Because of the inherent non-metal properties, mild reaction conditions, and broad functional group tolerance, the use of small organic compounds encoding and converting another organic component has developed into a remarkable process. C–H activation reactions, on the other hand, have already emerged as a powerful strategy for forming C–C and C–X (X= N, O, S) bonds. Combining organocatalysis and C-H bond functionalization is highly rational as two coexisting and rapidly growing research fields in modern synthetic chemistry, and the cooperative strength along this consistent has proven to be a successful way of making C-H bond functionalization much more feasible, reliable, and specific. At the same time, the synthesis of heterocyclic compounds is an important field in organic chemistry due to the vast application of heterocycles in pharmaceuticals, polymers, and material science. This mini-review describes the recent developments in the synthesis of heterocyclic compounds through the alliance of organocatalysis and C-H bond functionalizations.
杂环化合物合成中C-H键功能化的有机催化
有机催化是合成各种有机分子的一个重要且快速发展的领域。由于其固有的非金属性质、温和的反应条件和广泛的官能团耐受性,使用编码和转化另一种有机成分的小有机化合物已经发展成为一个了不起的过程。另一方面,C–H活化反应已经成为形成C–C和C–X(X=N,O,S)键的强大策略。有机催化和C-H键官能化作为现代合成化学中两个共存且快速发展的研究领域,是非常合理的,并且沿着这一一致性的合作强度已被证明是使C-H键功能化更加可行、可靠和特异的成功方法。同时,由于杂环在药物、聚合物和材料科学中的广泛应用,杂环化合物的合成是有机化学的一个重要领域。这篇小综述描述了通过有机催化和C-H键功能化的联盟合成杂环化合物的最新进展。
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来源期刊
Current Organocatalysis
Current Organocatalysis CHEMISTRY, PHYSICAL-
CiteScore
2.00
自引率
0.00%
发文量
28
期刊介绍: Current Organocatalysis is an international peer-reviewed journal that publishes significant research in all areas of organocatalysis. The journal covers organo homogeneous/heterogeneous catalysis, innovative mechanistic studies and kinetics of organocatalytic processes focusing on practical, theoretical and computational aspects. It also includes potential applications of organocatalysts in the fields of drug discovery, synthesis of novel molecules, synthetic method development, green chemistry and chemoenzymatic reactions. This journal also accepts papers on methods, reagents, and mechanism of a synthetic process and technology pertaining to chemistry. Moreover, this journal features full-length/mini review articles within organocatalysis and synthetic chemistry. It is the premier source of organocatalysis and synthetic methods related information for chemists, biologists and engineers pursuing research in industry and academia.
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