Screening tests for the evaluation of cognitive impairment in multiple sclerosis patients

Q4 Medicine

Romanian Journal of Neurology/ Revista Romana de Neurologie Pub Date : 2022-12-31 DOI:10.37897/rjn.2022.4.1

Alina Ioana Nacu-Florescu, O. Schreiner, T. Schreiner

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引用次数: 0

Abstract

Multiple sclerosis (MS), the most common autoimmune neurological disease of young people, is a significant burden for the patient, significantly decreasing the quality of life. Besides motor deficits, sensory problems, and vision loss, in recent years, neurologists have focused also on the cognitive impairment related to this condition. The early detection of cognitive disturbances is currently an essential part of MS patients’ follow-ups, as any worsening suggests the inefficiency of the applied treatment and the need for a therapeutic switch. In this regard, this review aims to highlight the importance of cognitive screening tests in the periodical evaluation of MS patients. While in the first part, the most frequently used cognitive screening tests in Romania are presented in a detailed manner, in the second part of the article, the clinical impact of these tests is highlighted, based on the results of the most relevant randomized clinical trials published during the last 10 years. Finally, the authors suggest future research directions to improve cognitive screening testing in MS patients after exposing the limitations of currently used screening batteries.

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评估多发性硬化症患者认知障碍的筛查试验

多发性硬化症（MS）是年轻人最常见的自身免疫性神经疾病，对患者来说是一个巨大的负担，会显著降低生活质量。除了运动缺陷、感觉问题和视力丧失外，近年来，神经学家还关注与这种情况相关的认知障碍。认知障碍的早期检测目前是多发性硬化症患者随访的重要组成部分，因为任何恶化都表明应用治疗的效率低下，需要进行治疗转换。在这方面，这篇综述旨在强调认知筛查测试在MS患者定期评估中的重要性。在第一部分中，详细介绍了罗马尼亚最常用的认知筛查测试，而在文章的第二部分中，根据过去10年中发表的最相关的随机临床试验的结果，强调了这些测试的临床影响。最后，作者在暴露了目前使用的筛查电池的局限性后，提出了改进MS患者认知筛查测试的未来研究方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Romanian Journal of Neurology/ Revista Romana de Neurologie Medicine-Neurology (clinical)

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

4 weeks

期刊介绍： ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.