Thin, soft, skin-integrated electronics for real-time and wireless detection of uric acid in sweat

IF 4.5 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

International Journal of Smart and Nano Materials Pub Date : 2023-07-24 DOI:10.1080/19475411.2023.2236997

Yue Hu, Lan Wang, Jian Li, Yawen Yang, G. Zhao, Yiming Liu, Xingcan Huang, Pengcheng Wu, Binbin Zhang, Yanli Jiao, Mengge Wu, Shengxin Jia, Qiang Zhang, Guoqiang Xu, Rui Shi, Dengfeng Li, Yingchun Li, Zhengchun Peng, Xinge Yu

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引用次数: 1

Abstract

ABSTRACT Wearable sweat sensors are gaining significant attention due to their unparalleled potential for noninvasive health monitoring. Sweat, as a kind of body fluid, contains informative physiological indicators that are related to personalized health status. Advances in wearable sweat sampling and routing technologies, flexible, and stretchable materials, and wireless digital technologies have led to the development of integrated sweat sensors that are comfortable, flexible, light, and intelligent. Herein, we report a flexible and integrated wearable device via incorporating a microfluidic system and a sensing chip with skin-integrated electronic format toward in-situ monitoring of uric acid (UA) in sweat that associates with gout, cardiovascular, and renal diseases. The microfluidic system validly realizes the real-time capture perspiration from human skin. The obtained detection range is 5–200 μM and the detection limit is 1.79 μM, which offers an importance diagnostic method for clinical relevant lab test. The soft and flexible features of the constructed device allows it to be mounted onto nearly anywhere on the body. We tested the sweat UA in diverse subjects and various body locations during exercise, and similar trends were also observed by using a commercial UA assay kit. undefined

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薄，软，皮肤集成电子实时和无线检测汗液中的尿酸

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来源期刊

International Journal of Smart and Nano Materials MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

6.30

自引率

5.10%

发文量

审稿时长

11 weeks

期刊介绍： The central aim of International Journal of Smart and Nano Materials is to publish original results, critical reviews, technical discussion, and book reviews related to this compelling research field: smart and nano materials, and their applications. The papers published in this journal will provide cutting edge information and instructive research guidance, encouraging more scientists to make their contribution to this dynamic research field.