A Case of Treatment-resistant Advanced Lung Cancer in a Patient with HIV Infection

Abstract

━━ Background. Antiretroviral therapy has been introduced to improve the prognosis of patients with human immunodeficiency virus (HIV) infection, and as a result, non-AIDS-defining cancer (NADC) may af-fect the prognosis. It has been shown that lung cancer patients with HIV progress faster in comparison to patients without HIV, and have a poor prognosis; however, there is no specific treatment protocol for lung cancer in patients with HIV. Case. The patient was a 55-year-old man who was diagnosed with advanced lung adenocarci-noma and infected with HIV. Platinum-based chemotherapy was administered, but the effect was poor, and docetaxel was started as the next treatment. He then showed prolonged myelosuppression, and his general condi-tion worsened, making it difficult to continue chemotherapy. Conclusion. We report a case of advanced lung cancer in a patient with HIV infection. It is hoped that standard chemotherapy for advanced lung cancer with HIV infection will be established.