The Relationship Between Metabolic Syndrome and Benign Prostate Enlargement: A Case-Control Study in a Peruvian Military Hospital.

IF 1 Q4 UROLOGY & NEPHROLOGY
Valeria Ugarte-Carbajal, José M Vela-Ruiz, Vela-Rui Guillen-Ponce, Lucy E Correa-López, Verónica Rubin-de-Celis, Jhony A De La Cruz-Vargas
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引用次数: 0

Abstract

Objective: This study aimed to determine how metabolic syndrome is related to benign prostatic enlargement in males under 60 years old in a national military hospital in Peru.

Materials and methods: We conducted a retrospective, quantitative, case-control study. By simple random sampling, 87 cases with benign prostatic enlargement and 174 controls were included, with a statistical power of 80%. The benign prostatic enlargement was evaluated by clinical picture and ultrasound and the metabolic syndrome was evaluated according to the Adult Treatment Panel III criteria. The statistical analysis was performed using the STATAv14 program, the chi-square statistical test was used and odds ratio was obtained, at a significance level of 5%.

Results: The mean age of the cases and controls was 55 (51-58) and 52 (46-57), respectively. By multivariate analysis, the factors related to benign prostatic enlargement were the presence of benign prostatic enlargement (adjusted odds ratio: 2.71, 95% CI: 1.27-5.80; P=.010), waist circumference ≥102 cm (adjusted odds ratio: 6.51, 95% CI: 3.09-13.71; P < .001), elevated fasting glucose (adjusted odds ratio: 1.38, 95% CI: 0.65-2.91; P=.399), high triglycerides (adjusted odds ratio: 5.29, 95%: CI 2.40-11.64; P < .001), and arterial hypertension (adjusted odds ratio: 4.67, 95% CI 2.19-9.95; P < .001). Elevated high-density lipoprotein cholesterol was a protective factor (adjusted odds ratio: 0.09, 95% CI: 0.04-0.20; P < .001).

Conclusion: The present study showed that metabolic syndrome and its components (waist circumference, hypertension, triglycerides, and high-density lipoprotein cholesterol) are factors related to benign prostatic enlargement in patients under 60 years old in a military hospital in Peruvian population. Waist circumference as an indicator of overweight/obesity is a practical anthropometric marker of interest in public health.

Abstract Image

代谢综合征与良性前列腺增生的关系:秘鲁某军事医院的病例对照研究
目的:本研究旨在确定代谢综合征与秘鲁国家军事医院60岁以下男性前列腺增生的关系。材料和方法:我们进行了一项回顾性、定量、病例对照研究。通过简单的随机抽样,87例良性前列腺肥大患者和174名对照者被包括在内,统计功效为80%。通过临床图片和超声评估良性前列腺肥大,并根据成人治疗小组III标准评估代谢综合征。使用STATAv14程序进行统计分析,使用卡方统计检验,获得优势比,显著性水平为5%。结果:病例和对照组的平均年龄分别为55岁(51-58岁)和52岁(46-57岁)。经多因素分析,与良性前列腺肥大相关的因素为良性前列腺肥大的存在(校正比值比:2.71,95%CI:1.27-5.80;P = .010)、腰围≥102cm(调整后比值比:6.51,95%CI:3.09-13.71;P<.001)、空腹血糖升高(调整后的比值比:1.38,95%CI:0.65-2.91;P = .399)、高甘油三酯(调整比值比:5.29,95%CI 2.40-11.64;P<.001),高密度脂蛋白胆固醇升高是一个保护因素(校正比值比:0.09,95%CI:0.04-0.20;P<.001)与秘鲁军队医院60岁以下患者的良性前列腺肥大有关。腰围作为超重/肥胖的指标,是公共卫生领域感兴趣的实用人体测量标志。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Turkish journal of urology
Turkish journal of urology Medicine-Urology
CiteScore
2.10
自引率
0.00%
发文量
53
期刊介绍: The aim of the Turkish Journal of Urology is to contribute to the literature by publishing scientifically high-quality research articles as well as reviews, editorials, letters to the editor and case reports. The journal’s target audience includes, urology specialists, medical specialty fellows and other specialists and practitioners who are interested in the field of urology.
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