Complex Treatment of the Patients with Cerebral Palsy Using Fetal Stem Cells

N. Sych, M. Klunnyk, I. Matiyashchuk, M. Demchuk, O. Ivankova, Andriy Sinelnyk, M. Skalozub, Khrystyna Sorochunska
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引用次数: 2

Abstract

Objective: The aim of this study was to examine fetal stem cells (FSCs) treatment safety and efficacy in complex therapy for cerebral palsy (CP) children. We studied clinical, neurological, and laboratory changes in CP patients before and after FSCs therapy. Materials and methods: 11 children diagnosed with CP were under observation in Cell Therapy Center EmCell including 6 boys aged from 2 to 13 years, whose mean age was 4.23 ± 0.24 yrs. and 5 girls aged from 2.5 to 12 years with mean age which constituted 3.92 ± 0.15 yrs. The patients were allocated to the Main Group (MG) who along with standard treatment received FSCs. Control group (CG) included 9 patients suffering from CP who underwent treatment solely with inclusion of conventional methods and consisted of 4 males (aged from 3 to 14 yrs. whose average age made up 4.01 ± 0.12 yrs.) and 5 females in age from 3 to 15 yrs. with mean age by 3.87 ± 0.18 yrs. FSCs were administered as a complex therapy for the patients with CP and the data of clinical and laboratory investigations were analyzed during the whole study period. Results: It has been identified that patients who were administered treatment by use of FSCs revealed improvements of their immune status. Conclusion: FSCs use in complex treatment of patients with CP stabilizes disease compensation and leads to improvement of immune blood findings.
胎儿干细胞综合治疗脑瘫
目的:本研究的目的是检验胎儿干细胞(FSCs)在脑瘫(CP)儿童综合治疗中的安全性和有效性。我们研究了CP患者在FSCs治疗前后的临床、神经和实验室变化。材料和方法:11名被诊断为CP的儿童在细胞治疗中心EmCell接受观察,其中6名男孩年龄在2至13岁之间,平均年龄为4.23±0.24岁,5名女孩年龄在2.5至12岁之间,其平均年龄为3.92±0.15岁。对照组(CG)包括9名CP患者,他们只接受了常规方法的治疗,包括4名男性(年龄在3-14岁,平均年龄为4.01±0.12岁)和5名女性,年龄在3-15岁,平均岁为3.87±0.18岁。FSCs是CP患者的一种复杂治疗方法,并对整个研究期间的临床和实验室调查数据进行了分析。结果:已经确定,通过使用FSCs进行治疗的患者的免疫状态有所改善。结论:FSCs用于CP患者的综合治疗稳定了疾病补偿,并改善了免疫血液检查结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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