Prevalence, Demographic, Clinical Characteristics and Outcomes of Elderly Patients with Community Acquired Pneumonia Admitted in a Tertiary Medical Center: A Retrospective Cohort Study

B BernalShirleyPaz, Santiaguel Joel, L. Adolf
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引用次数: 1

Abstract

Objectives: To determine the prevalence, demographic data, clinical characteristics, microbiologic profile, clinical outcomes and risk factors of mortality among elderly with Community Acquired Pneumonia (CAP). Methods: This study was a retrospective cohort analysis utilizing data from January to December of 2018 among 159 elderly patients admitted with CAP in a tertiary hospital in the Philippines. Demographics, clinical characteristics, microbiologic profile was assessed using percentage and frequency. Chi-square test was used to compare factors to age group and risk factors of mortality were determined using binary logistic regression analysis. Results: The overall prevalence of elderly patients admitted with CAP was 5% and was noted to be higher in females (55.35%) than males (44.65%). Majority belonged to aged 6574 years (36.5%). The most common pathogen identified is Escherichia coli (17.24%) and Streptococcus parasanguinis (17.17%) in blood and sputum culture, respectively. Risk factors significantly associated to mortality were history of alcoholic drinking, renal disease, oxygen saturation < 90% upon admission, decrease sensorium, hypotension, lung findings of retractions and decrease breath sounds, Escherichia coli in blood culture and mixed bacterial coinfection in sputum culture (p < 0.05). Conclusion: CAP is a common problem with clinical impact to elderly patients. The study was able to provide prevalence, demographic data and clinical characteristics associated with mortality among elderly patients admitted due to CAP. This study can also guide clinicians and hospital personnel in infection control and management strategies.
三级医疗中心收治的老年社区获得性肺炎患者的患病率、人口统计学、临床特征和转归:一项回顾性队列研究
目的:确定老年社区获得性肺炎(CAP)患者的患病率、人口统计学数据、临床特征、微生物学特征、临床结果和死亡风险因素。方法:本研究利用2018年1月至12月的数据,对菲律宾一家三级医院收治的159名CAP老年患者进行了回顾性队列分析。使用百分比和频率评估人口统计学、临床特征和微生物特征。卡方检验用于比较各年龄组的因素,并使用二元逻辑回归分析确定死亡率的危险因素。结果:老年CAP患者的总患病率为5%,女性(55.35%)高于男性(44.65%)。大多数患者年龄为6574岁(36.5%)。血液和痰培养中最常见的病原体分别是大肠杆菌(17.24%)和副血链球菌(17.17%)。与死亡率显著相关的危险因素有酗酒史、肾病、入院时血氧饱和度<90%、感觉减退、低血压、肺部收缩和呼吸音降低,血液培养中的大肠杆菌和痰培养中的混合细菌合并感染(p<0.05)。结论:CAP是老年患者常见的临床影响问题。该研究能够提供因CAP入院的老年患者的患病率、人口统计数据和与死亡率相关的临床特征。这项研究也可以指导临床医生和医院工作人员的感染控制和管理策略。
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