Exacerbation of pre-existence psoriasis following immune checkpoint inhibitor treatment

Abstract

Immune checkpoint inhibitors are currently developed for the treatment of cancers showing high efficacy even in the cases of advanced and persistent malignancies. Psoriasis has been reported as a rare irAE in both the exacerbation of preexisting psoriasis and the novel onset psoriasis during immunotherapy. Herein, we report a case of pre-existence psoriasis, which was exacerbated following the administration of immune checkpoint inhibitors. We also summarize case reports and conducted a review of the literature.