Cardiometabolic Diseases: A Global Perspective

G. Rao
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引用次数: 13

Abstract

The George Institute for Global Health of Australia, in their website claim that the epidemic of cardio-metabolic diseases is escalating worldwide, including India. The rapid socioeconomic transition is believed to have contributed to this rise, with the individuals being increasingly exposed to energy-dense foods, high stress levels, and sedentary work habits. Larry Husten in an article in Lancet wrote, that in 1960, the typical heart-attack“victim” was a middle-class US or European executive. Cardiovascular Disease (CVD) was largely unknown in the developing world, but now, a global epidemic of CVD is underway. In the 21st century, say epidemiologists, a typical patient presenting with heart attack will be a Moscow Taxi driver, or a Bombay factory worker [1]. Underlying causes may or may not be the same at each demography. For instance, another article written in the same year, drew the attention of this prediction. Larry Husten contemplated on the enormous rise in deaths from heart disease in Russia. The author of this article points out to the fact, that to a large extent, the pattern of alcohol consumption may play a big role in the cardiovascular deaths in Russia [2]. Since 1980, incidence of obesity has increased by two-fold and diabetes by four-fold worldwide, according to the NCD Risk Factor Collaborators report [3,4]. Hypertension is one of the primary risk factors for heart disease and stroke. Over 875 million were hypertensives in the year 2000 and will double by the year 2025 [5]. Another factor to be considered when discussing from a global perspective, is that nearly two-thirds of individuals with CMDs live in lowand middle-income countries. On the other hand, immigrant population is increasing rapidly in several countries, because of the economic attractiveness and public infrastructure. Just look at the UAE as an example, they have more immigrants than the native Arabs. Although conventional cardiovascular risk factors such as smoking, blood pressure and total cholesterol predict risk within these ethnic groups, they do not fully account for the differences in risk, between ethnic groups, suggesting that alternative explanations might exist. We feel strongly, that there is a great need to investigate the prevalence and pattern of metabolic risks in general, identify the unique risk factors responsible for development and/or progression of these condition’s and the economic and social costs for the treatment of these diseases. All of these metabolic diseases have risen to the status of an epidemic, and cost of combating these diseases will pose, in the very near future, a great economic burden to the global community.
心脏代谢疾病:全球视野
澳大利亚乔治全球健康研究所在其网站上声称,包括印度在内的全球心脏代谢疾病的流行正在升级。快速的社会经济转型被认为是导致这一增长的原因,人们越来越多地接触到高能量食物、高压力和久坐不动的工作习惯。Larry Husten在《柳叶刀》上的一篇文章中写道,1960年,典型的心脏病发作“受害者”是美国或欧洲的中产阶级高管。心血管疾病(CVD)在发展中国家基本上是未知的,但现在,CVD的全球流行正在进行。流行病学家说,在21世纪,典型的心脏病发作患者将是莫斯科出租车司机或孟买工厂工人[1]。在每个人口统计学中,根本原因可能相同,也可能不同。例如,同年写的另一篇文章引起了人们对这一预测的注意。拉里·胡斯滕(Larry Husten)对俄罗斯心脏病死亡人数的大幅上升进行了思考。本文作者指出,在很大程度上,饮酒模式可能在俄罗斯心血管死亡中发挥重要作用[2]。根据NCD风险因素合作者的报告[3,4],自1980年以来,全球范围内肥胖的发病率增加了两倍,糖尿病增加了四倍。高血压是心脏病和中风的主要危险因素之一。2000年,超过8.75亿人患有高血压,到2025年将翻一番[5]。从全球角度进行讨论时需要考虑的另一个因素是,近三分之二的CMD患者生活在中低收入国家。另一方面,由于经济吸引力和公共基础设施,一些国家的移民人口正在迅速增加。以阿联酋为例,他们的移民比土生土长的阿拉伯人多。尽管吸烟、血压和总胆固醇等传统心血管风险因素可以预测这些种族群体的风险,但它们并不能完全解释种族群体之间的风险差异,这表明可能存在其他解释。我们强烈认为,非常需要调查代谢风险的普遍性和模式,确定导致这些疾病发展和/或进展的独特风险因素,以及治疗这些疾病的经济和社会成本。所有这些代谢性疾病都已上升为流行病,在不久的将来,抗击这些疾病的成本将给全球社会带来巨大的经济负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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