Anti–oxidant and anti-inflammation activities of nanostructured assemblies of silver sulfide nanoparticles using an extract of Cinnamomum tamala leaves

Abstract

Silver sulfide nanoparticles have gained applications in industrial areas due to their tunable physical, chemical, and biological properties. Among various nanoparticles silver sulfide nanoparticles have gained worldwide attention due to their assessment as an anti-microbial agent. The microstructure of nanostructured silver sulfide nanoparticles determine its electronic, structural, optical and electrical properties, and possible applications of silver sulfide nanoparticles in modern electronics, biology and medicine. The appearance of nonstoichiometry in silver sub-lattices of monoclinic silver sulfide at decreasing size particles to the nanometer scale is considered. The interdependent changes in non-stoichiometry and crystal structure at the transformation of a non- conducting nano crystalline silver sulfide in super-ionic conductors are also very important aspects in biosynthesis of Silver sulfide nanoparticles. The effect of nano crystalline state on the peculiarities of crystal structure, non-stoichiometry, optical and thermal properties of bio synthesized Silver sulfide nanoparticles are explained. Silver sulfide nanoparticle have provide a significant role in the biomedical field for various application- oriented products such as IR cameras, solar panels, optical fiber and filters. Among modern biomedical potential of silver sulfide nanoparticles tremendous interest is oriented towards the therapeutically enhanced personalized health care practices. The biosynthesized silver sulfide nanoparticle using aqueous extract of Cinnamomum leaves has been documented in our present research work. The presence of secondary metabolites like flavonoid, tannins, steroid, cardiac glycosides, and alkaloids was confirmed by phytochemical analyses of the aqueous extract of Cinnamomum tamala leaves and these secondary metabolites can be used as reducing stabilizing and capping agent. After three months, the biosynthesized Silver sulfide nanoparticles were found to be stable without the evidence of agglomeration at room temperature. Structural and morphological properties of Silver sulfide nanoparticles were analyzed by UV-VIS, FT-IR, XRD, EDX, TEM, and SEM spectroscopic techniques. The surface Plasmon resonance for Silver sulfide nanoparticles was obtained around 290nm. Biosynthesized Silver sulfide nanoparticles was spherical in shape with effective diameter size of 50nm.Our novel approach provides a promising and effective method to large scale synthesis of eco-friendly, and cost effective pharmacologically active silver sulfide nano particles.