Production of Biodegradable Metal Foams by Powder Metallurgy Method

IF 1.8 4区材料科学 Q2 MATERIALS SCIENCE, CHARACTERIZATION & TESTING

Physical Mesomechanics Pub Date : 2023-04-19 DOI:10.1134/S102995992302008X

G. Demir, D. Akyurek, A. Hassoun, I. Mutlu

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引用次数: 1

Abstract

In this study, highly porous biocompatible and biodegradable zinc, iron and magnesium alloy foams were fabricated for temporary implant and scaffold applications. Specimens with open porous structure were fabricated by powder metallurgy based space holder method. Mg, Fe and Zn are the main bioabsorable metals. Mg alloys biodegrade too fast with H₂ evolution. Biodegradation rate of Fe alloys is too slow, and by-products remain inside the body. Zn alloys show biodegradation rates in the middle of Mg and Fe alloys, and their biodegradation by-products are bioresorbable. Here several Fe, Zn, and Mg alloys were manufactured, and comparatively characterized. Effects of alloying elements on biodegradation, corrosion and mechanical properties were investigated separately. As the mechanical properties of temporary implants must decrease slowly, the variation of mechanical properties with time in the foams was investigated. Corrosion performance was tested in simulated body fluid. Biodegradation rate was investigated by using weight loss and metal ion release measurements. The corrosion and biodegradation rates of Zn specimens were lower than in Mg specimens and higher than in Fe specimens. Fe²⁺, Zn²⁺ and Mg²⁺ ion release amounts were lower than the upper limit for humans.

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粉末冶金法制备可生物降解金属泡沫

在本研究中，制备了高度多孔的生物相容性和可生物降解的锌、铁和镁合金泡沫，用于临时植入和支架应用。采用基于粉末冶金的空间支架法制备开孔结构试样。镁、铁和锌是主要的生物可吸收金属。镁合金生物降解速度过快，产生氢气。铁合金的生物降解速度太慢，副产品留在体内。锌合金的生物降解率在Mg和Fe合金中间，其生物降解副产物具有生物可吸收性。本文制备了几种铁、锌、镁合金，并对其进行了比较表征。分别研究了合金元素对生物降解、腐蚀和力学性能的影响。由于临时植入物的力学性能下降缓慢，研究了泡沫体中力学性能随时间的变化。在模拟体液中测试了腐蚀性能。通过失重和金属离子释放测量来研究生物降解率。Zn试样的腐蚀速率和生物降解速率低于Mg试样，高于Fe试样。Fe2+、Zn2+和Mg2+离子释放量低于人体上限。

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来源期刊

Physical Mesomechanics Materials Science-General Materials Science

CiteScore

3.50

自引率

18.80%

发文量

期刊介绍： The journal provides an international medium for the publication of theoretical and experimental studies and reviews related in the physical mesomechanics and also solid-state physics, mechanics, materials science, geodynamics, non-destructive testing and in a large number of other fields where the physical mesomechanics may be used extensively. Papers dealing with the processing, characterization, structure and physical properties and computational aspects of the mesomechanics of heterogeneous media, fracture mesomechanics, physical mesomechanics of materials, mesomechanics applications for geodynamics and tectonics, mesomechanics of smart materials and materials for electronics, non-destructive testing are viewed as suitable for publication.