Propiolic acids in the synthesis of N-heterocycles

IF 1.9 4区化学 Q2 CHEMISTRY, ORGANIC

Mini-reviews in Organic Chemistry Pub Date : 2022-08-04 DOI:10.2174/1570193x19666220804145501

Zhanyong Wang, Zhantong Liu, Nan Wang, Yuan-feng Tong

引用次数: 0

Abstract

This review discussed the synthetic applications of propiolic acids in the preparation of diverse N-heterocycles. 3~9-membered rings like azirines, β-lactams, oxazolidin-2-ones, 2-oxindoles, indoles, isoindolin-1-ones, imidazo[1,2-a]pyridines, triazoles, 2-pyridones, 2-quinolones, 1,4-benzothiazines, thiazinones, spiroindolines et al could be constructed via radical addition, four-component Ugi reactions, 1,3-dipolar cycloadditions, or Diels-Alder reaction mechanism. We hope this review will promote future research in this area. • Introduction

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丙酸在N-杂环合成中的应用

综述了丙酸在制备各种n -杂环化合物中的合成应用。3~9元环可以通过自由基加成、四组分Ugi反应、1,3-偶极环加成或diols - alder反应机制构建，如氮嘧啶、β-内酰胺、恶唑烷-2-酮、2-氧吲哚、吲哚、异吲哚-1-酮、咪唑[1,2-a]吡啶、三唑、2-吡啶酮、2-喹诺酮、1,4-苯并噻唑、噻嗪酮、螺吲哚啉等。我们希望这篇综述能促进这一领域未来的研究。•介绍

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mini-reviews in Organic Chemistry 化学-有机化学

CiteScore

4.50

自引率

4.30%

发文量

116

审稿时长

>12 weeks

期刊介绍： Mini-Reviews in Organic Chemistry is a peer reviewed journal which publishes original reviews on all areas of organic chemistry including organic synthesis, bioorganic and medicinal chemistry, natural product chemistry, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly, without any charges. The journal encourages submission of reviews on emerging fields of organic chemistry including: Bioorganic Chemistry Carbohydrate Chemistry Chemical Biology Chemical Process Research Computational Organic Chemistry Development of Synthetic Methodologies Functional Organic Materials Heterocyclic Chemistry Macromolecular Chemistry Natural Products Isolation And Synthesis New Synthetic Methodology Organic Reactions Organocatalysis Organometallic Chemistry Theoretical Organic Chemistry Polymer Chemistry Stereochemistry Structural Investigations Supramolecular Chemistry