{"title":"COVID-19: Vaccine and antimicrobial resistance what are the global implications?","authors":"J. Robinson, Alexandra Leclézio, I. Banerjee","doi":"10.3126/JAIM.V10I1.37099","DOIUrl":null,"url":null,"abstract":"Antimicrobial resistance is a worldwide and highly quantified risk to global health and is more prevalent than resistance developed in vaccines as both antimicrobial resistance and vaccine resistance develop in different settings and because of alternate mechanisms. Vaccines act as a preventative measure and allow the immune system to kill any pathogen in the initial phases when the load is relatively low. This circumvents the replication of the pathogen and thus prevents the formation of mutations and furthermore resistance which is attributed to those mutations. Mutations in the target and or binding sites of a said therapeutic regime confer resistance more often in antimicrobials than they do vaccines. to counter new variants as they arise will be an ongoing process. It is evident in future that new vaccines to the mutations in COVID-19 may have to be developed as they are for the seasonal influenzae virus.","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"10 1","pages":"51-53"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in internal medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3126/JAIM.V10I1.37099","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Antimicrobial resistance is a worldwide and highly quantified risk to global health and is more prevalent than resistance developed in vaccines as both antimicrobial resistance and vaccine resistance develop in different settings and because of alternate mechanisms. Vaccines act as a preventative measure and allow the immune system to kill any pathogen in the initial phases when the load is relatively low. This circumvents the replication of the pathogen and thus prevents the formation of mutations and furthermore resistance which is attributed to those mutations. Mutations in the target and or binding sites of a said therapeutic regime confer resistance more often in antimicrobials than they do vaccines. to counter new variants as they arise will be an ongoing process. It is evident in future that new vaccines to the mutations in COVID-19 may have to be developed as they are for the seasonal influenzae virus.