Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia

Nigerian Journal of Medicine Pub Date : 2023-01-01 DOI:10.4103/njm.njm_126_22

A. Yunus, M. Odigbo, S. Tasiu, SM Babangida, Yakubu Yunusa, Am Kabiru, MM Yusuf

{"title":"Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia","authors":"A. Yunus, M. Odigbo, S. Tasiu, SM Babangida, Yakubu Yunusa, Am Kabiru, MM Yusuf","doi":"10.4103/njm.njm_126_22","DOIUrl":null,"url":null,"abstract":"Background: Inhalational anaesthetics are used for the induction and maintenance of general anaesthesia in children. More agents are evolving in an effort to discover the agent of choice in this age group, considering the safety margin, availability, affordability, and accessibility of the anaesthetics. Aim: The aim of our study was to compare the qualities of halothane and sevoflurane in paediatric patients. Materials and Methods: This was a prospective randomised study of 100 children within the age group of 5–12 years, scheduled for elective surgery in Ahmadu Bello University Teaching Hospital, Zaria, from January to October 2022, and satisfied the study inclusion criteria. The following variables (heart rate, blood pressure, arrhythmias, and complications) were recorded and analysed using IBM SPSS version 25 (Chicago) USA. P ≤ 0.05 was considered statistically significant. Results: The incidence of tolerability at induction of anaesthesia, hypoxaemia (SpO2 <90%), and airway responses (laryngospasm, coughing, and breath holding) was similar in both the groups. However, at induction of anaesthesia, the degree of muscle rigidity in the sevoflurane group was statistically significant compared with the halothane group (P = 0.028), but the difference was not statistically significant at the recovery period (P = 0.59). More so, the incidence of arrhythmias was higher in the halothane group than in the sevoflurane group. Conclusion: The overall qualities of halothane were commensurate with that of sevoflurane. However, where available and affordable, sevoflurane will be a better agent of choice in paediatric anaesthesia.","PeriodicalId":52572,"journal":{"name":"Nigerian Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nigerian Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/njm.njm_126_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Inhalational anaesthetics are used for the induction and maintenance of general anaesthesia in children. More agents are evolving in an effort to discover the agent of choice in this age group, considering the safety margin, availability, affordability, and accessibility of the anaesthetics. Aim: The aim of our study was to compare the qualities of halothane and sevoflurane in paediatric patients. Materials and Methods: This was a prospective randomised study of 100 children within the age group of 5–12 years, scheduled for elective surgery in Ahmadu Bello University Teaching Hospital, Zaria, from January to October 2022, and satisfied the study inclusion criteria. The following variables (heart rate, blood pressure, arrhythmias, and complications) were recorded and analysed using IBM SPSS version 25 (Chicago) USA. P ≤ 0.05 was considered statistically significant. Results: The incidence of tolerability at induction of anaesthesia, hypoxaemia (SpO2 <90%), and airway responses (laryngospasm, coughing, and breath holding) was similar in both the groups. However, at induction of anaesthesia, the degree of muscle rigidity in the sevoflurane group was statistically significant compared with the halothane group (P = 0.028), but the difference was not statistically significant at the recovery period (P = 0.59). More so, the incidence of arrhythmias was higher in the halothane group than in the sevoflurane group. Conclusion: The overall qualities of halothane were commensurate with that of sevoflurane. However, where available and affordable, sevoflurane will be a better agent of choice in paediatric anaesthesia.

查看原文本刊更多论文

七氟烷和氟烷在儿科麻醉中的质量比较

背景：吸入麻醉药用于儿童全身麻醉的诱导和维持。考虑到麻醉剂的安全边际、可用性、可负担性和可及性，越来越多的麻醉剂正在发展，以努力发现该年龄组的首选药剂。目的：我们研究的目的是比较氟烷和七氟醚在儿科患者中的质量。材料和方法：这是一项前瞻性随机研究，涉及100名5-12岁年龄组的儿童，计划于2022年1月至10月在扎里亚的艾哈迈杜·贝洛大学教学医院进行选择性手术，符合研究纳入标准。以下变量（心率、血压、心律失常和并发症）使用IBM SPSS 25版（芝加哥）USA进行记录和分析。P≤0.05被认为具有统计学意义。结果：两组在麻醉诱导、低氧血症（SpO2<90%）和气道反应（喉痉挛、咳嗽和屏气）时的耐受性发生率相似。然而，在麻醉诱导时，七氟醚组的肌肉僵硬程度与氟烷组相比具有统计学意义（P=0.028），但在恢复期差异无统计学意义（P=0.59）。更重要的是，氟烷组的心律失常发生率高于七氟醚组。结论：氟烷的总体质量与七氟醚相当。然而，在可用且价格合理的情况下，七氟烷将是儿科麻醉中更好的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nigerian Journal of Medicine

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： The Nigerian Journal of Medicine publishes articles on socio-economic, political and legal matters related to medical practice; conference and workshop reports and medical news.