8S, 9R)-Dihydroisoflavipucine, a New Isoflavipucine Derivative from the Endophytic Fungi Botryosphaeria dothidea

IF 1.5 4区生物学 Q3 CHEMISTRY, APPLIED

Records of Natural Products Pub Date : 2022-10-25 DOI:10.25135/rnp.360.2206.2500

Zhangshuang Deng, Hui Chen, Wendan Li, Liangmin Xue, Xiu-Jin Liu, Yiqing Zhou

引用次数: 1

Abstract

: A new isoflavipucine derivative, (8 S , 9 R )-dihydroisoflavipucine ( 1 ), is isolated from an ethyl acetate extract of endophytic fungi Botryosphaeria dothidea (D4-2) derived from Taxus mairei . The structure of 1 is elucidated based on nuclear magnetic resonance, circular dichroism, and mass spectrometry. The antiproliferative activity of the isolates against breast cancer cells MDA-MB-231, MCF7 and 4T1 are evaluated.

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8S，9R）-二氢异黄精，一种新的内生真菌Botryosphaeria dothidea的异黄精衍生物

从红豆杉内生真菌Botryosphaeria dothidea (D4-2)的乙酸乙酯萃取物中分离得到一个新的异黄嘌呤衍生物(8 S, 9 R)-二氢异黄嘌呤(1)。基于核磁共振、圆二色性和质谱分析对1的结构进行了分析。研究了分离物对乳腺癌细胞MDA-MB-231、MCF7和4T1的抗增殖活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Records of Natural Products 生物-医药化学

CiteScore

3.10

自引率

26.30%

发文量

审稿时长

4 months

期刊介绍： Records of Natural Products is a journal of natural product chemistry. Reviews, book reviews, research papers and short reports are considered on the substances of plants, microbes and animals. Discussions on the structure elucidation, synthesis of naturally occurring compounds and biological activity of natural compounds and plant extracts, biosynthesis of natural products and essential oils of aromatic plants as well as chemotaxonomy in the field of plants are welcomed in the journal. All published research articles in Records of Natural Products have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by expert referees.