Rice Malt: A Solvent-Catalyst for the Synthesis of N-Substituted Pyrroles

IF 0.9 Q4 CHEMISTRY, PHYSICAL

Current Organocatalysis Pub Date : 2023-05-16 DOI:10.2174/2213337210666230516151722

B. Banik, R. N. Yadav, T. Rohand

引用次数: 0

Abstract

The synthesis of diverse N-substituted pyrroles utilizing rice malt is identified. The reaction of hexane-2,5-dione with various primary amines develops the intriguing pyrrole scaffold in moderate to good yields. Method: The reaction was carried out at room to ambient temperature in an extremely environmentally benign condition, without the need for any additional solvents or catalysts. Result: In the synthesis of N-derivatized pyrroles, several 1°amines, both cyclic and acyclic residue, have been accomplished. Conclusion: To the best of my knowledge, no study has been reported so far based on Paal-Knorr pyrrole synthesis utilizing rice malt as a catalyst and solvent.

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米麦芽:合成n -取代吡咯的溶剂催化剂

鉴定了利用米麦芽合成不同N-取代吡咯的方法。己烷-2,5-二酮与各种伯胺的反应以中等至良好的产率形成了有趣的吡咯支架。方法：反应在室温至环境温度下，在极为环保的条件下进行，不需要任何额外的溶剂或催化剂。结果：在N-衍生吡咯的合成中，已经完成了几种1°胺，包括环状和非环状残基。结论：据我所知，目前还没有关于以大米麦芽为催化剂和溶剂合成帕尔-克诺尔吡咯的研究报告。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Organocatalysis CHEMISTRY, PHYSICAL-

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： Current Organocatalysis is an international peer-reviewed journal that publishes significant research in all areas of organocatalysis. The journal covers organo homogeneous/heterogeneous catalysis, innovative mechanistic studies and kinetics of organocatalytic processes focusing on practical, theoretical and computational aspects. It also includes potential applications of organocatalysts in the fields of drug discovery, synthesis of novel molecules, synthetic method development, green chemistry and chemoenzymatic reactions. This journal also accepts papers on methods, reagents, and mechanism of a synthetic process and technology pertaining to chemistry. Moreover, this journal features full-length/mini review articles within organocatalysis and synthetic chemistry. It is the premier source of organocatalysis and synthetic methods related information for chemists, biologists and engineers pursuing research in industry and academia.