Rabies Virus Infection: A Case Series and Literature Review

IF 0.3 Q4 PEDIATRICS
Shiva Shadani, Fahimeh Ghasemi, Mahsa Kamali, Mohammad Reza Navaeifar, A. Alikhani, S. Alian, Ali Reza Davoudi Badabi, M. S. Rezai
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引用次数: 0

Abstract

Background: Rabies is a fatal and often neglected disease leading to encephalomyelitis following a bite by an infected mammal. According to the necessity of rabies disease in Iran, we present four cases of rabies virus infection. Case Presentation: We presented 4 cases of rabies virus infection hospitalized in different hospitals in Iran in 2021-2022. Three patients were male. The youngest patient was 6 years old and the oldest was 81 years old. In all 4 cases, RT-PCR detected the positive virus infection. Three cases received rabies immunoglobulin. All of them received at least one dose of rabies vaccination; but, unfortunately, all patients died. Conclusions: The present case series showed the necessity of early rabies vaccination and also the early organization of stray dogs in the community. Unfortunately, two cases were lost to follow-up. So, the population education and follow-up of suspected rabies patients must be taken seriously by healthcare facilities.
狂犬病病毒感染病例系列及文献综述
背景:狂犬病是一种致命且经常被忽视的疾病,在被感染的哺乳动物咬伤后会导致脑脊髓炎。根据伊朗狂犬病的必要性,我们报告了四例狂犬病病毒感染病例。病例介绍:我们介绍了2021-2022年在伊朗不同医院住院的4例狂犬病病毒感染病例。三名患者为男性。年龄最小的患者为6岁,年龄最大的患者为81岁。在所有4例病例中,RT-PCR检测到阳性病毒感染。3例接受狂犬病免疫球蛋白治疗。所有人都至少接种了一剂狂犬病疫苗;但是,不幸的是,所有的病人都死了。结论:本系列病例表明了早期接种狂犬病疫苗的必要性,也表明了早期组织社区流浪狗的必要性。不幸的是,有两个病例在随访中丢失。因此,医疗机构必须认真对待疑似狂犬病患者的人群教育和随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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