HBA1C level and its role on ischemic stroke patients with prediabetes

Q4 Medicine

Romanian Journal of Neurology/ Revista Romana de Neurologie Pub Date : 2023-06-30 DOI:10.37897/rjn.2023.2.11

Abdul Gofir, Raymond Aris Nimrod Alvonsius Silalahi, K. Dananjoyo, Ismail Setyopranoto

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引用次数: 0

Abstract

Background. Stroke is the highest cause of death in Indonesia. Impaired glucose tolerance becomes one of the metabolic risk factors that contribute to ischemic stroke. This study will observe the role of HbA1c level on ischemic stroke in “Dr. Sardjito” General Hospital due to limited research data of this aspect in Indonesia. Objective. The objective of this study is to explore the role of HbA1c level on ischemic stroke in prediabetic patients of “Dr. Sardjito” General Hospital, Yogyakarta. Method. This study design is non-experimental, observational study with correlation analysis approach. The research collected 106 data of non-diabetic and prediabetic ischemic stroke patients’ medical records in “Dr. Sardjito” General Hospital, recorded from 2012 until 2015. Result. A Comparison of HbA1c level in prediabetic ischemic stroke patients were significantly higher (p<0.001), compared to non-diabetic ischemic stroke patients (mean rank 80.00 vs. 27.00). Multivariate analysis was performed and showed elevated HbA1c level, modified with decreased diastolic blood pressure, associated 70.8% in determining ischemic stroke in prediabetic patients of “Dr. Sardjito” General Hospital. Conclusion. Elevated HbA1c level, modified with decreased diastolic blood pressure, has significant predisposition role on ischemic stroke patients with prediabetes in “Dr. Sardjito” General Hospital.

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HBA1C水平及其在缺血性卒中伴糖尿病前期患者中的作用

背景中风是印尼死亡人数最多的疾病。糖耐量受损成为导致缺血性中风的代谢危险因素之一。由于印尼这方面的研究数据有限，本研究将在“Sardjito医生”综合医院观察HbA1c水平在缺血性中风中的作用。客观的本研究的目的是探讨HbA1c水平在日惹“Sardjito医生”综合医院糖尿病前期患者缺血性卒中中的作用。方法本研究设计为非实验性、观察性研究，采用相关分析方法。该研究收集了2012年至2015年在“Sardjito医生”综合医院记录的106份非糖尿病和糖尿病前期缺血性中风患者的医疗记录数据。后果糖尿病前期缺血性卒中患者的HbA1c水平与非糖尿病缺血性卒中患者相比显著升高（p＜0.001）（平均排名80.00对27.00），与“Dr.Sardjito”综合医院糖尿病前期患者缺血性卒中的确定相关70.8%。结论在“Sardjito医生”综合医院，HbA1c水平升高，舒张压降低，对糖尿病前期缺血性中风患者具有重要的易感性作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Romanian Journal of Neurology/ Revista Romana de Neurologie Medicine-Neurology (clinical)

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

4 weeks

期刊介绍： ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.