Assessment of the severity of the condition of patients with acute substance poisoning using the PSS scale

Q4 Medicine

HIV Infection and Immunosuppressive Disorders Pub Date : 2023-04-30 DOI:10.22328/2077-9828-2023-15-1-60-66

A. H. Lodyagin, E. Rakhmanova, A. Miroshnichenko

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Abstract

Objective. To determine the effectiveness and introduce the Poisoning Severity Score (PSS) scale into the clinical practice of the department for patients with acute poisoning with psychoactive substances.Materials and methods. A single–center retrospective and prospective randomized clinical trial was conducted in 200 patients with acute poisoning with the psychostimulant alpha-pyrrolidinopentiophenone and the synthetic cannabinoid MDMB–FUBINACA. To assess the severity of substance poisoning, the Poisoning Severity Score (PSS) scale developed by the European Association of Clinical Toxicologists IPCS/EC/EAPCCT was used.Results and discussion. This scale allows to objectify clinical and laboratory manifestations of acute poisoning with psychodisleptics, to identify the leading syndromes, to predict the risk of complications and emergency conditions.Conclusion. The PSS scale is easy to use and does not require a wide range of diagnostic capabilities from a medical institution, helps to determine the tactics of patient management and determines the volume of emergency care at the hospital stage.

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应用PSS量表评价急性物质中毒患者病情严重程度

客观的确定精神活性物质急性中毒患者的有效性，并将中毒严重程度评分（PSS）量表引入该科的临床实践。材料和方法。在200名急性中毒患者中进行了一项单中心回顾性和前瞻性随机临床试验，研究对象为精神刺激剂α-吡咯烷酮和合成大麻素MDMB–FUBINACA。为了评估物质中毒的严重程度，使用了由欧洲临床毒理学协会IPCS/EC/EAPCT开发的中毒严重程度评分（PSS）量表。结果和讨论。该量表可以客观化精神病患者急性中毒的临床和实验室表现，识别主要综合征，预测并发症和紧急情况的风险。结论PSS量表易于使用，不需要医疗机构提供广泛的诊断能力，有助于确定患者管理策略，并确定医院阶段的急救量。

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来源期刊

HIV Infection and Immunosuppressive Disorders Medicine-Infectious Diseases

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.