Interaction of Antitumor Agent Mitoxantrone with Double Helical Synthetic Polyribonucleotides Poly(G)⋅Poly(C) and Poly(I)⋅Poly(C)

Y. Babayan, S. Hakobyan, R. S. Ghazaryan, M. Shahinyan
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Abstract

The interaction of antitumor drug mitoxantrone (MTX) with double-stranded synthetic RNA homopolymers has been studied by means of spectroscopic (UV-Visible absorption, circular dichroism) technique...
抗肿瘤药米托蒽醌与双螺旋合成聚核糖核苷酸Poly(G)⋅Poly(C)和Poly(I)⋅Poly(C)的相互作用
采用紫外-可见吸收、圆二色性等光谱技术研究了抗肿瘤药物米托蒽醌(MTX)与双链合成RNA均聚物的相互作用。
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