The impact of promoting revised UK low-risk drinking guidelines on alcohol consumption: interrupted time series analysis

J. Holmes, E. Beard, Jamie Brown, A. Brennan, I. Kersbergen, P. Meier, S. Michie, A. Stevely, Penny Buykx
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Previously, the guideline stated that men should not regularly consume more than 3–4 units per day and women should not regularly consume more than 2–3 units per day.\n \n \n \n To evaluate the impact of promoting revised UK drinking guidelines on alcohol consumption.\n \n \n \n Interrupted time series analysis of observational data.\n \n \n \n England, March 2014 to October 2017.\n \n \n \n A total of 74,388 adults aged ≥ 16 years living in private households in England.\n \n \n \n Promotion of revised UK low-risk drinking guidelines.\n \n \n \n Primary outcome – alcohol consumption measured by the Alcohol Use Disorders Identification Test – Consumption score. Secondary outcomes – average weekly consumption measured using graduated frequency, monthly alcohol consumption per capita adult (aged ≥ 16 years) derived from taxation data, monthly number of hospitalisations for alcohol poisoning (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision: T51.0, T51.1 and T51.9) and assault (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision: X85–Y09), and further measures of influences on behaviour change.\n \n \n \n The Alcohol Toolkit Study, a monthly cross-sectional survey and NHS Digital’s Hospital Episode Statistics.\n \n \n \n The revised drinking guidelines were not subject to large-scale promotion after the initial January 2016 announcement. An analysis of news reports found that mentions of the guidelines were mostly factual, and spiked during January 2016. In December 2015, the modelled average Alcohol Use Disorders Identification Test – Consumption score was 2.719 out of 12.000 and was decreasing by 0.003 each month. After the January 2016 announcement, Alcohol Use Disorders Identification Test – Consumption scores did not decrease significantly (β = 0.001, 95% confidence interval –0.079 to 0.099). However, the trend did change significantly such that scores subsequently increased by 0.005 each month (β = 0.008, 95% confidence interval 0.001 to 0.015). This change is equivalent to 0.5% of the population moving each month from drinking two or three times per week to drinking four or more times per week. Secondary analyses indicated that the change in trend began 6 months before the guideline announcement. The secondary outcome measures showed conflicting results, with no significant changes in consumption measures and no substantial changes in influences on behaviour change, but immediate reductions in hospitalisations of 7.3% for assaults and 15.4% for alcohol poisonings.\n \n \n \n The pre-intervention data collection period was only 2 months for influences on behaviour change and the graduated frequency measure. Our conclusions may be generalisable only to scenarios in which guidelines are announced but not promoted.\n \n \n \n The announcement of revised UK low-risk drinking guidelines was not associated with clearly detectable changes in drinking behaviour. Observed reductions in alcohol-related hospitalisations are unlikely to be attributable to the revised guidelines. Promotion of the guidelines may have been prevented by opposition to the revised guidelines from the government's alcohol industry partners or because reduction in alcohol consumption was not a government priority or because practical obstacles prevented independent public health organisations from promoting the guidelines. Additional barriers to the effectiveness of guidelines may include low public understanding and a need for guidelines to engage more with how drinkers respond to and use them in practice.\n \n \n \n Current Controlled Trials ISRCTN15189062.\n \n \n \n This project was funded by the National Institute for Health Research (NIHR) Public Health Research programme and will be published in full in Public Health Research; Vol. 8, No. 14. 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引用次数: 1

Abstract

The UK’s Chief Medical Officers revised the UK alcohol drinking guidelines in 2016 to ≤ 14 units per week (1 unit = 10 ml/8 g ethanol) for men and women. Previously, the guideline stated that men should not regularly consume more than 3–4 units per day and women should not regularly consume more than 2–3 units per day. To evaluate the impact of promoting revised UK drinking guidelines on alcohol consumption. Interrupted time series analysis of observational data. England, March 2014 to October 2017. A total of 74,388 adults aged ≥ 16 years living in private households in England. Promotion of revised UK low-risk drinking guidelines. Primary outcome – alcohol consumption measured by the Alcohol Use Disorders Identification Test – Consumption score. Secondary outcomes – average weekly consumption measured using graduated frequency, monthly alcohol consumption per capita adult (aged ≥ 16 years) derived from taxation data, monthly number of hospitalisations for alcohol poisoning (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision: T51.0, T51.1 and T51.9) and assault (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision: X85–Y09), and further measures of influences on behaviour change. The Alcohol Toolkit Study, a monthly cross-sectional survey and NHS Digital’s Hospital Episode Statistics. The revised drinking guidelines were not subject to large-scale promotion after the initial January 2016 announcement. An analysis of news reports found that mentions of the guidelines were mostly factual, and spiked during January 2016. In December 2015, the modelled average Alcohol Use Disorders Identification Test – Consumption score was 2.719 out of 12.000 and was decreasing by 0.003 each month. After the January 2016 announcement, Alcohol Use Disorders Identification Test – Consumption scores did not decrease significantly (β = 0.001, 95% confidence interval –0.079 to 0.099). However, the trend did change significantly such that scores subsequently increased by 0.005 each month (β = 0.008, 95% confidence interval 0.001 to 0.015). This change is equivalent to 0.5% of the population moving each month from drinking two or three times per week to drinking four or more times per week. Secondary analyses indicated that the change in trend began 6 months before the guideline announcement. The secondary outcome measures showed conflicting results, with no significant changes in consumption measures and no substantial changes in influences on behaviour change, but immediate reductions in hospitalisations of 7.3% for assaults and 15.4% for alcohol poisonings. The pre-intervention data collection period was only 2 months for influences on behaviour change and the graduated frequency measure. Our conclusions may be generalisable only to scenarios in which guidelines are announced but not promoted. The announcement of revised UK low-risk drinking guidelines was not associated with clearly detectable changes in drinking behaviour. Observed reductions in alcohol-related hospitalisations are unlikely to be attributable to the revised guidelines. Promotion of the guidelines may have been prevented by opposition to the revised guidelines from the government's alcohol industry partners or because reduction in alcohol consumption was not a government priority or because practical obstacles prevented independent public health organisations from promoting the guidelines. Additional barriers to the effectiveness of guidelines may include low public understanding and a need for guidelines to engage more with how drinkers respond to and use them in practice. Current Controlled Trials ISRCTN15189062. This project was funded by the National Institute for Health Research (NIHR) Public Health Research programme and will be published in full in Public Health Research; Vol. 8, No. 14. See the NIHR Journals Library website for further project information.
推广修订后的英国低风险饮酒指南对酒精消费的影响:中断时间序列分析
英国首席医疗官于2016年将英国饮酒指南修订为≤ 每周14台(1台 = 10 ml/8 g乙醇)。此前,该指南指出,男性每天的摄入量不应超过3-4个单位,女性每天的摄入量也不应超过2-3个单位。评估推广修订后的英国饮酒指南对酒精消费的影响。观测数据的中断时间序列分析。英格兰,2014年3月至2017年10月。共有74388名年龄≥ 在英国的私人家庭生活了16年。推广修订后的英国低风险饮酒指南。主要结果——通过酒精使用障碍识别测试测量的饮酒量——饮酒量得分。次要结果——使用分级频率测量的平均每周饮酒量,人均成年人(年龄≥ 16年)和攻击(国际疾病和相关健康问题统计分类,第十次修订:T51.0、T51.1和T51.9)得出的每月酒精中毒住院人数,以及进一步衡量对行为改变的影响。酒精工具包研究,一项月度横断面调查和NHS Digital的医院事件统计。在2016年1月首次宣布后,修订后的饮酒指南没有得到大规模推广。对新闻报道的分析发现,对该指南的提及大多是事实,并在2016年1月激增。2015年12月,模拟的平均酒精使用障碍识别测试-消费得分为2.719(满分12.000),每月下降0.003。在2016年1月公布后,酒精使用障碍识别测试-消费分数没有显著下降(β = 0.001,95%置信区间-0.079至0.099)。然而,趋势确实发生了显著变化,分数随后每月增加0.005(β = 0.008,95%置信区间0.001至0.015)。这一变化相当于0.5%的人口每月从每周饮酒两到三次转变为每周饮酒四到四次以上。二次分析表明,趋势的变化始于指南发布前6个月。次要结果指标显示出相互矛盾的结果,消费指标没有显著变化,对行为改变的影响也没有实质性变化,但袭击和酒精中毒的住院人数立即减少了7.3%和15.4%。干预前的数据收集期仅为2个月,用于对行为变化和分级频率测量的影响。我们的结论可能仅适用于公布但未推广指导方针的情况。修订后的英国低风险饮酒指南的宣布与饮酒行为的明显变化无关。观察到的与酒精相关的住院人数减少不太可能归因于修订后的指南。政府的酒精行业合作伙伴反对修订后的指南,或者减少饮酒量不是政府的优先事项,或者由于实际障碍阻碍了独立的公共卫生组织推广指南,这些都可能阻碍了指南的推广。指南有效性的其他障碍可能包括公众理解度低,以及需要更多地参与饮酒者如何应对和在实践中使用指南。当前对照试验ISRCTN15189062。该项目由国家卫生研究所公共卫生研究计划资助,并将在《公共卫生研究》上全文发表;第8卷第14期。有关更多项目信息,请访问NIHR期刊图书馆网站。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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