Oncocytic Adrenocortical Carcinoma: A Rare Case Report

Abstract

Oncocytic neoplasms can be seen in various organs, but they are usually detected in the thyroid, salivary glands, and kidneys. They contain oncocytic tumor cells that are recognized by their broad, eosinophilic and granular cytoplasm due to anomalous mitochondrial collection (1). Oncocytic neoplasms of the adrenal gland are uncommon and are generally benign and nonfunctioning. These tumors are more common in women and on the left adrenal gland. To date, 147 cases have been reported (2). Recent reports indicate that about 20% of the adrenocortical oncocytic neoplasms show malignant components and 10-20% produce hormones which may cause symptoms of Cushing’s syndrome or virilism (3).