APPLICATIONS OF CHITOSAN–GRAPHENE OXIDE NANOCOMPOSITES IN MEDICAL SCIENCE: A REVIEW

IF 0.8 Q4 MATERIALS SCIENCE, BIOMATERIALS

Progress on Chemistry and Application of Chitin and its Derivatives Pub Date : 2018-09-10 DOI:10.15259/PCACD.23.001

K. Pieklarz, M. Tylman, Z. Modrzejewska

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引用次数: 8

Abstract

Combinations of biopolymers with nanostructured carbon materials have been the subject of interest of many scientists in recent years. Particularly significant are nanocomposites made of chitosan, which is a linear aminopolysaccharide obtained in the process of deacetylation of chitin, and graphene oxide (GO). These systems, due to the atypical properties of both components such as non-toxicity, biocompatibility with human tissues and organs as well as bacteriostaticity, are characterised by a wide range of biomedical applications. They may be used in emergency medicine as dressing materials which accelerate wound healing, as well as carriers of drugs/genes and biological macromolecules, for example proteins, peptides and nucleic acids. In addition, CS-GO systems can potentially be used in regenerative medicine as scaffolds for cell culture. For this reason, the current publication presents the possibilities of the application of chitosan–graphene oxide nanocomposites in medicine considering the characteristics of the system components.

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壳聚糖-氧化石墨烯纳米复合材料在医学中的应用综述

生物聚合物与纳米结构碳材料的结合是近年来许多科学家感兴趣的课题。特别重要的是由壳聚糖和氧化石墨烯(GO)制成的纳米复合材料。壳聚糖是几丁质去乙酰化过程中得到的一种线性氨基多糖。由于两种成分的非典型特性，如无毒性、与人体组织和器官的生物相容性以及抑菌性，这些系统具有广泛的生物医学应用。它们可用于急诊医学，作为加速伤口愈合的敷料，以及药物/基因和生物大分子的载体，例如蛋白质、多肽和核酸。此外，CS-GO系统还可以作为细胞培养的支架用于再生医学。因此，考虑到系统组分的特性，当前的出版物提出了壳聚糖-氧化石墨烯纳米复合材料在医学上应用的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Progress on Chemistry and Application of Chitin and its Derivatives MATERIALS SCIENCE, BIOMATERIALS-

CiteScore

1.10

自引率

16.70%

发文量

期刊介绍： Progress in the Chemistry and Application of Chitin and its Derivatives is an annual journal focused on all aspects of production, modification, enzymology and application of chitin and its many derivatives, including chitosan. The journal publishes full-length papers as well as invited reviews. To be considered, papers must present original research that has not been published or accepted for publication elsewhere. The language of the journal will be English.