Amine Ouaket, Boutaina Addoum, B. E. Khalfi, A. Soukri, N. Knouzi, M. Berrada
{"title":"Investigation of antioxidant activity of some bis-benzimidazole in Tetrahymena thermophila stressed cells","authors":"Amine Ouaket, Boutaina Addoum, B. E. Khalfi, A. Soukri, N. Knouzi, M. Berrada","doi":"10.48317/IMIST.PRSM/MORJCHEM-V9I2.20868","DOIUrl":null,"url":null,"abstract":"In this paper, we present experimental findings on the protective effect of some bis-benzimidazole molecules against oxidative (H 2 O 2 ) and nitrosative (SNP) stress using the protozoan T. thermophila as a cellular model. The results of this article show that the molecules 2,2’-Benzendiyl-1,4-Bis-(5-amino-1H-benzimidazole) and 2,2’-Octandiyl-1,8-Bis-(quinolin-8-ol-5-azo-1H-benzimidazole) have a protective effect against stress important than the molecule 2,2’-Benzendiyl-1,4-Bis-(1H-benzimidazole).","PeriodicalId":18768,"journal":{"name":"Moroccan Journal of Chemistry","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2021-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Moroccan Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.48317/IMIST.PRSM/MORJCHEM-V9I2.20868","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 3
Abstract
In this paper, we present experimental findings on the protective effect of some bis-benzimidazole molecules against oxidative (H 2 O 2 ) and nitrosative (SNP) stress using the protozoan T. thermophila as a cellular model. The results of this article show that the molecules 2,2’-Benzendiyl-1,4-Bis-(5-amino-1H-benzimidazole) and 2,2’-Octandiyl-1,8-Bis-(quinolin-8-ol-5-azo-1H-benzimidazole) have a protective effect against stress important than the molecule 2,2’-Benzendiyl-1,4-Bis-(1H-benzimidazole).