Dosimetric analysis of 3D-printing non-coplanar template combined with CT-guided125I seed implantation for the treatment of spinal metastasis

中华放射肿瘤学杂志 Pub Date : 2020-02-15 DOI:10.3760/CMA.J.ISSN.1004-4221.2020.02.010

Jian Cui, Yuliang Jiang, Z. Ji, F. Guo, R. Peng, Haitao Sun, J. Fan, Weiyan Li

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Abstract

Objective To compare the preoperative and postoperative dosimetric parameters in the treatment of spinal metastasis, and to verify the accuracy of 3D-printing non-coplanar template (3D-PNCT) combined with CT-guided 125I seed implantation for the treatment of spinal metastasis. Methods The treatment plans of 7 patients with spinal metastasis (9 lesions) from 2016 to 2018 receiving 3D-PNCT in combination with CT-guided 125I seed implantation were retrospectively analyzed. The dosimetric parameters including homogeneity index (HI), conformal index (CI), external index (EI), dose of 90% target volume(D90), mPD, volume percent of 100%, 150%, and 200% prescribed dose V100、V150、V200 and D2cm3 of spinal cord were compared before and after operation. The british columbia cancer ageny particle implantation quality evaluation standard was applied to evaluate the quality of implantation. Results The HI, EI and CI, D90, mPD, V100, V150, V200 and D2cm3 of spinal cord did not significantly differ before and after the plan (all P>0.05). Five were evaluated as excellent and 4 were assessed as good. Conclusion The postoperative dosimetric parameters of 3D-PNCT combined with CT guided 125I seed implantation of spinal metastasis are basically consistent with preoperative dosimetric parameters. The postoperative plans are evaluated as excellent or good, suggesting that the technology has a good therapeutic accuracy in the treatment of spinal metastasis. Key words: 3D-printing non-coplanar template; Seed implantation; Spinal metastasis; Dosimetry

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3D打印非共面模板联合CT引导下125I种子植入治疗脊柱转移瘤的剂量分析

目的比较治疗脊柱转移的术前、术后剂量学参数，验证3d打印非共面模板(3D-PNCT)联合ct引导下125I粒子植入治疗脊柱转移的准确性。方法回顾性分析2016 - 2018年7例脊柱转移患者(9个病灶)行3D-PNCT联合ct引导下125I粒子植入的治疗方案。比较术前、术后脊髓均匀性指数(HI)、适形指数(CI)、外指数(EI)、90%靶体积剂量(D90)、mPD、100%、150%、200%规定剂量体积百分比V100、V150、V200、D2cm3的剂量学参数。采用不列颠哥伦比亚省癌症机构粒子植入质量评价标准对植入质量进行评价。结果治疗前后脊髓HI、EI、CI、D90、mPD、V100、V150、V200、D2cm3差异无统计学意义(P < 0.05)。5个评价为优秀，4个评价为良好。结论3D-PNCT联合CT引导下125I粒子植入脊柱转移瘤术后剂量学参数与术前剂量学参数基本一致。术后方案被评价为优秀或良好，表明该技术在治疗脊柱转移方面具有良好的治疗准确性。关键词:3d打印非共面模板;种子植入;脊柱转移;剂量测定法

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来源期刊

中华放射肿瘤学杂志

自引率

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发文量

6375

期刊介绍： The Chinese Journal of Radiation Oncology is a national academic journal sponsored by the Chinese Medical Association. It was founded in 1992 and the title was written by Chen Minzhang, the former Minister of Health. Its predecessor was the Chinese Journal of Radiation Oncology, which was founded in 1987. The journal is an authoritative journal in the field of radiation oncology in my country. It focuses on clinical tumor radiotherapy, tumor radiation physics, tumor radiation biology, and thermal therapy. Its main readers are middle and senior clinical doctors and scientific researchers. It is now a monthly journal with a large 16-page format and 80 pages of text. For many years, it has adhered to the principle of combining theory with practice and combining improvement with popularization. It now has columns such as monographs, head and neck tumors (monographs), chest tumors (monographs), abdominal tumors (monographs), physics, technology, biology (monographs), reviews, and investigations and research.