Metabolic Syndrome and Its Components Are Associated with Frailty: A Nationwide Population-Based Study in Taiwan

Abstract

Methods: The cross-sectional study comprised of 1,006 communityliving middle and old-age Taiwanese. Metabolic syndrome defined by using National Cholesterol Education Programme Adult Treatment Panel III guidelines. A frailty index of 35 items derived basing on the standard principles of frailty index development. As opposed to the usual method, frailty index (FI) ≤0.08 denoted non-frail; FI ≥0.25 indicated frail; the rest were pre-frail. Multivariable logistic regression analysis was employed to investigate associations between frailty and metabolic syndrome.