Patterns of malignancies in patients with HIV-AIDS: a single institution observational study

The Journal of community and supportive oncology Pub Date : 2018-09-01 DOI:10.12788/JCSO.0416

R. Haleshappa

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引用次数: 2

Abstract

India has the third largest HIV epidemic in the world because of its large population size, with 0.3% of the adult population infected with HIV. at translates to 2.1 million infected people, posing a signicant challenge in the management of these individuals.1 In all, 43% of the infected are currently on highly active antiretroviral therapy (HAART).1 ere has been a signicant decrease in the number of HIV-AIDS–related deaths in recent years because of the remarkable increase in the use of antiretroviral therapy.2 However, the prolonged life expectancy in these patients has resulted in an increase in the risk of various new diseases such as cancers. With the complex interactions between altered immunity and infections, the risk of cancers is markedly increased in patients with HIV-AIDS.3 e spectrum of malignancies in this group of patients diers from that in the general population. In addition, the pattern and the magnitude of malignancies dier in dierent parts of the world.4 In this study, we have analyzed the pattern of malignancies in patients with HIVAIDS in a regional cancer center in India. e aim of the study was to analyze the pattern of malignancies in patients with HIV-AIDS based on their age and sex and to document the CD4 counts at the time the malignancy was diagnosed.

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HIV-AIDS患者恶性肿瘤的模式：一项单一机构的观察性研究

印度是世界上第三大艾滋病毒流行国，因为其人口众多，0.3%的成年人口感染了艾滋病毒。at相当于210万感染者，这对这些人的管理构成了重大挑战。1总的来说，43%的感染者目前正在接受高活性抗逆转录病毒疗法（HAART）。1近年来，由于抗逆转录病毒治疗的使用显著增加，与艾滋病毒/艾滋病相关的死亡人数显著减少。2然而，这些患者的预期寿命延长导致了患癌症等各种新疾病的风险增加。由于免疫力的改变和感染之间的复杂相互作用，HIV-AIDS患者患癌症的风险显著增加。这组患者的恶性肿瘤谱与普通人群不同。此外，世界不同地区恶性肿瘤的模式和程度也不同。4在这项研究中，我们分析了印度癌症地区中心HIVAIDS患者的恶性肿瘤模式。本研究的目的是根据年龄和性别分析HIV-AIDS患者的恶性肿瘤模式，并记录诊断恶性肿瘤时的CD4计数。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Journal of community and supportive oncology

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