Clinical application of animal based extracellular matrix in hernioplasty

Abstract

Biological scaffolds are composed of natural ECM (extracellular matrix) due to their origin from animal-based proteinous molecules; they have efficient in the potential of therapeutic applications. The ECM has full potential which increases constructive remodeling. The structural and functional molecules of ECM are capable to establish proper attachment or communication with an adjacent environment of healing area of injury. Their biocompatibility is responsible for positive signaling to recipient own matrix formation.1 The ECM degradation with the promotion of native matrix is another property which makes it an ideal biomaterial.2