Adherence to antiretroviral therapy mediates the link between posttraumatic stress disorder symptoms and health-related quality of life

IF 1.9 4区心理学 Q2 PSYCHOLOGY, MULTIDISCIPLINARY

South African Journal of Psychology Pub Date : 2021-10-05 DOI:10.1177/00812463211048122

D. U. Onu

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引用次数: 1

Abstract

Human immunodeficiency virus is one of the trauma-inducing chronic illnesses with attendant-negative impact on health-related quality of life. Substantial literature exists on the association of posttraumatic stress disorder symptoms and health-related quality of life among people living with human immunodeficiency virus, but little is known about the pathways explaining this link. This study therefore examined the mediating role of adherence to antiretroviral therapy in the association between posttraumatic stress disorder symptoms and health-related quality of life among people living with human immunodeficiency virus. Nine hundred and sixty-nine people living with human immunodeficiency virus in Nigeria who were on antiretroviral therapy completed measures of posttraumatic stress disorder symptoms, adherence to antiretroviral therapy, and health-related quality of life. Hayes PROCESS macro for SPSS was used to analyse the data. Adherence to antiretroviral therapy mediated the association between posttraumatic stress disorder symptoms and health-related quality of life in the relationship and treatment impact domains, implying that poor adherence to antiretroviral therapy is a pathway through which posttraumatic stress disorder symptoms exert negative influence on health-related quality of life of people living with human immunodeficiency virus. Interventions aimed at reducing the impact of posttraumatic stress disorder symptoms on quality of life of people living with human immunodeficiency virus should focus on improving clients’ level of adherence to antiretroviral therapy treatment.

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坚持抗逆转录病毒疗法介导创伤后应激障碍症状与健康相关生活质量之间的联系

人类免疫缺陷病毒是一种创伤性慢性疾病，对健康相关的生活质量产生负面影响。关于人类免疫缺陷病毒感染者的创伤后应激障碍症状与健康相关生活质量之间的关系，已有大量文献存在，但对解释这种联系的途径知之甚少。因此，本研究考察了抗逆转录病毒治疗依从性在人类免疫缺陷病毒感染者创伤后应激障碍症状与健康相关生活质量之间的关联中的中介作用。在尼日利亚，接受抗逆转录病毒治疗的969名人类免疫缺陷病毒感染者完成了创伤后应激障碍症状、抗逆转录病毒治疗依从性和与健康有关的生活质量的测量。采用SPSS的Hayes PROCESS宏对数据进行分析。在关系和治疗影响域中，坚持抗逆转录病毒治疗介导了创伤后应激障碍症状与健康相关生活质量之间的关联，这意味着抗逆转录病毒治疗依从性差是创伤后应激障碍症状对人类免疫缺陷病毒感染者健康相关生活质量产生负面影响的一个途径。旨在减少创伤后应激障碍症状对人类免疫缺陷病毒感染者生活质量影响的干预措施，应侧重于提高患者对抗逆转录病毒治疗的坚持程度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

South African Journal of Psychology PSYCHOLOGY, MULTIDISCIPLINARY-

CiteScore

3.40

自引率

10.50%

发文量

期刊介绍： The South African Journal of Psychology publishes contributions in English from all fields of psychology. While the emphasis is on empirical research, the Journal also accepts theoretical and methodological papers, review articles, short communications, reviews and letters containing fair commentary. Priority is given to articles which are relevant to Africa and which address psychological issues of social change and development.