Therapeutic drug monitoring of teicoplanin in a patient with bloodstream infection by Enterococcus faecium

Abstract

Objective： To analyze the blood concentration，efficacy and adverse drug reactions（ADRs） of teicoplanin in treatment of bloodstream infection by Enterococcus faecium.Methods： Changes in physiological and pathological indexes of the patient were closely followed and recorded，and the treatment regimen was adjusted according to the results of therapeutic drug monitoring（TDM） of teicoplanin.Results： In the light of the results of therapeutic drug monitoring of teicoplanin，bloodstream infection was cured，pathogenic microorganism was effectively eliminated and no ADRs occurred.Conclusion： With TDM，teicoplanin could be safely and effectively used in the treatment of blood stream infection.