Effects of Heat and WiFi (2.4 GHz) Exposure on Rat Cardiovascular System

IF 0.6 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
M. Jafari, Ehsan Masoudi, N. Sotoudeh, S. F. Hosseini
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引用次数: 0

Abstract

Background: Today, wireless communication systems are destructive with increased lipid peroxidation and oxidation state and have adverse biological effects on human health. Objectives: In this study, we examined the effects of exposure to WiFi wireless frequency (2.4 GHz) on histopathological changes in the cardiovascular system of rats. Methods: The experimental groups included 32 adult male rats divided into control (not exposed to heat and WiFi), WiFi (exposed to 2.45 GHz for 52 consecutive days (2 h/day)), heat (water bath of 43°C for 52 consecutive days (10 min/day)), and heat+WiFi groups (exposed to 2.45 GHz then water bath of 43°C). On the 52nd day, the heart was removed, and its total volume and weight were determined using stereological techniques. The number of cardiomyocytes nuclei and the volume of the myocardium were determined. Blood samples were collected to measure reduced glutathione (GSH) content, Total Antioxidant Capacity (TAC), and malondialdehyde level (MDA). Data were analyzed by ANOVA, Kruskal-Wallis, and Mann-Whitney U tests. Results: The heart weight and volume density of the myocardium increased in the WiFi-irradiated group compared to the control group (P < 0.05). Also, exposure to WiFi increased MDA levels and decreased TAC and GSH compared to the control group (P < 0.05). Conclusions: This study indicated that RFW might cause structural changes and oxidative stress in the heart. Also, exposure to radiofrequency decreased total antioxidant activity in heart tissue with histological changes, including myocardium hypertrophy and decreased number of myocytes.
高温和WiFi (2.4 GHz)暴露对大鼠心血管系统的影响
背景:如今,无线通信系统具有破坏性,脂质过氧化和氧化状态增加,并对人类健康产生不利的生物学影响。目的:在本研究中,我们检测了暴露于WiFi无线频率(2.4GHz)对大鼠心血管系统组织病理学变化的影响。方法:实验组包括32只成年雄性大鼠,分为对照组(不暴露于高温和WiFi)、WiFi组(暴露于2.45GHz连续52天(2小时/天))、高温组(43°C水浴52天(10分钟/天)和高温+WiFi组(先暴露于2.45 GHz,再暴露于43°C热水浴)。第52天,取出心脏,用体视学技术测定其总体积和重量。测定心肌细胞核的数量和心肌体积。采集血样以测定还原型谷胱甘肽(GSH)含量、总抗氧化能力(TAC)和丙二醛(MDA)水平。数据通过ANOVA、Kruskal-Wallis和Mann-Whitney U检验进行分析。结果:与对照组相比,WiFi照射组心肌重量和体积密度增加(P<0.05),暴露于WiFi后MDA水平升高,TAC和GSH降低(P<0.01)。结论:RFW可能引起心脏结构变化和氧化应激。此外,暴露于射频会降低心脏组织的总抗氧化活性,并伴有组织学变化,包括心肌肥大和心肌细胞数量减少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Health Scope
Health Scope PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
自引率
16.70%
发文量
34
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