Therapeutic Potential of Gut Microbiota in Child Health

Q4 Medicine

Anti-Infective Agents Pub Date : 2023-05-18 DOI:10.2174/2211352521666230518115214

K. Pathak, Ratnadeep Bhattacharjee, J. Das, S. Bordoloi, M. Pathak, Pervej Alom Barbhuiya, RiyaSaikia

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引用次数: 0

Abstract

Gut or intestinal microbiota inhabit our body and are well nurtured by the body’s ambiance of its preference. Gut microorganisms include bacteria, archae, and fungi that primarily inhabit the digestive tracts of animals. Bacteria like Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12 have been studied on a wide scale for their potential therapeutic applications. These bacteria are used as probiotics, most often as dietary supplements. They increase the population of the gut microbiota required for normal metabolic activities of the body. Recently, efforts have been made to analyze the effects of these probiotics and gut microbiota in the treatment of various diseases in children. In recent years, research has been conducted to investigate the effects of probiotics and microbiota in the gut on the prevention and treatment of a wide range of childhood disorders. Studies have been carried out to investigate the gut microbiota's effects on the function of beta cells in children recently diagnosed with type 1 diabetes. In this review article, a few applications and research of microbiota on children have been highlighted.

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肠道菌群在儿童健康中的治疗潜力

肠道或肠道微生物群栖息在我们的身体中，并受到身体所偏爱的环境的良好滋养。肠道微生物包括细菌、古菌和真菌，它们主要栖息在动物的消化道中。鼠李糖乳杆菌GG和乳酸双歧杆菌Bb12等细菌因其潜在的治疗应用而被广泛研究。这些细菌被用作益生菌，最常被用作膳食补充剂。它们增加了人体正常代谢活动所需的肠道微生物群的数量。最近，人们开始努力分析这些益生菌和肠道菌群在治疗儿童各种疾病中的作用。近年来，研究人员对肠道益生菌和微生物群在预防和治疗多种儿童疾病中的作用进行了研究。已经开展了研究，以调查肠道微生物群对最近诊断为1型糖尿病的儿童的β细胞功能的影响。本文就微生物群在儿童中的应用及研究进展作一综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Anti-Infective Agents Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

1.50

自引率

0.00%

发文量

期刊介绍： Anti-Infective Agents publishes original research articles, full-length/mini reviews, drug clinical trial studies and guest edited issues on all the latest and outstanding developments on the medicinal chemistry, biology, pharmacology and use of anti-infective and anti-parasitic agents. The scope of the journal covers all pre-clinical and clinical research on antimicrobials, antibacterials, antiviral, antifungal, and antiparasitic agents. Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services.