1-Cyanoacetylthiosemicarbazides: Recent Advances In Their Synthesis, Reactivity In Heterocyclization, And Bio Applications

IF 1.9 4区化学 Q2 CHEMISTRY, ORGANIC

Mini-reviews in Organic Chemistry Pub Date : 2023-05-29 DOI:10.2174/1570193x20666230529155754

S. Bondock, Nada Alabbad, Aisha Hossana, M. Abdou

引用次数: 0

Abstract

The synthesis of 1-cyanoacetylthiosemicarbazides is at the apex attention of researchers due to their multifaced reactivity as versatile precursors in the synthesis of mono-, bi-, and fused_heterocyclic compounds as well as metal complexes. Despite this, no comprehensive survey was, so far, dedicated to the synthesis, chemical transformation, and bioactivities of this relevant family of synthetic organic precursors and their derivatives. The present survey aims to summarize an up-to-date record of the preparation of 1-cyanoacetylthiosemicarbazides and their chemical transformation. A particular focus is given to their metal complexes and bio applications

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1-氰基乙酰基硫代氨基叠氮化物的合成、杂环反应性及其生物应用研究进展

1-氰乙酰基硫代氨基脲的合成受到了研究人员的高度关注，因为它们具有多面反应性，可以作为合成单、双、融合杂环化合物和金属配合物的多功能前体。尽管如此，到目前为止，还没有对这一相关家族的合成有机前体及其衍生物的合成、化学转化和生物活性进行全面的调查。本文综述了1-氰乙酰基硫代氨基脲的制备及其化学转化的最新研究进展。特别关注的是它们的金属配合物和生物应用

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mini-reviews in Organic Chemistry 化学-有机化学

CiteScore

4.50

自引率

4.30%

发文量

116

审稿时长

>12 weeks

期刊介绍： Mini-Reviews in Organic Chemistry is a peer reviewed journal which publishes original reviews on all areas of organic chemistry including organic synthesis, bioorganic and medicinal chemistry, natural product chemistry, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly, without any charges. The journal encourages submission of reviews on emerging fields of organic chemistry including: Bioorganic Chemistry Carbohydrate Chemistry Chemical Biology Chemical Process Research Computational Organic Chemistry Development of Synthetic Methodologies Functional Organic Materials Heterocyclic Chemistry Macromolecular Chemistry Natural Products Isolation And Synthesis New Synthetic Methodology Organic Reactions Organocatalysis Organometallic Chemistry Theoretical Organic Chemistry Polymer Chemistry Stereochemistry Structural Investigations Supramolecular Chemistry