Generalized HIV-associated kaposi's sarcoma with multiorgan lesion in a comorbid patient

Q4 Medicine
A. Khryanin, D. V. Kapustin, A. P. Nadeev, V. Sturov, E. V. Pushkarev
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引用次数: 0

Abstract

An important role in a number of different clinical manifestations of HIV infection is played by the pathology of the skin and mucous membranes. Kaposi sarcoma (KS) is a multifocal malignant tumor of vascular origin with a predominant lesion of the skin and involvement of internal organs. Prior to the development of the HIV epidemic, KS was considered a rare tumor. Under conditions of increasing immunosuppression, HIV-associated KS tends to have a more severe course, generalization, and is accompanied by damage to visceral organs, leading to the death of patients. The authors demonstrate a clinical case of generalized KS with lesions of the skin, mucous membranes and internal organs (lungs) in a patient with HIV infection. The pulmonary form of KS is rare, but often leads to death.
一名合并症患者的全身性HIV相关卡波西肉瘤伴多器官病变
皮肤和粘膜的病理学在HIV感染的许多不同临床表现中发挥着重要作用。卡波西肉瘤(KS)是一种血管源性多灶性恶性肿瘤,主要累及皮肤和内脏。在艾滋病流行之前,KS被认为是一种罕见的肿瘤。在免疫抑制增强的条件下,HIV相关的KS往往有更严重的病程、更普遍,并伴有内脏器官损伤,导致患者死亡。作者证明了一例HIV感染患者的皮肤、粘膜和内脏(肺)病变的全身性KS临床病例。肺型KS是罕见的,但经常导致死亡。
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来源期刊
HIV Infection and Immunosuppressive Disorders
HIV Infection and Immunosuppressive Disorders Medicine-Infectious Diseases
CiteScore
0.70
自引率
0.00%
发文量
37
期刊介绍: In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.
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